Chirality-pure carbon nanotubes show distinct complexation with recognition DNA sequences
Chirality-pure carbon nanotubes show distinct complexation with recognition DNA sequences
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纯手性碳纳米管与识别 DNA 序列表现出明显的络合
DOI：
10.1016/j.carbon.2020.06.040
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发表时间：
2020
期刊：
影响因子：
10.9
通讯作者：
Ao, Geyou
中科院分区：
文献类型：
--
作者：
Xhyliu, Fjorela;Ao, Geyou
纯手性单壁碳纳米管(SWCNTs)与识别DNA序列非共价络合，在水环境中表现出独特的相互作用行为和杂化稳定性。DNA包裹的SWCNTs的络合作用是DNA序列和SWCNT手性结构的强烈作用，突出表现在一对(6，5)对映体在强表面活性剂的作用下，相同的识别DNA序列被不同的涂层置换。通过表面活性剂交换，观察到不同的碳纳米管识别对的一系列变化，包括纳米管近红外光致发光强度从1.3倍增加到14.7倍，由DNA置换动力学得出的时间常数从9°S增加到230°S。CTC3TC-(7，6)杂化的时间常数为230°S，近红外发射强度相对较小地增加了4.4倍，突显了短DNA序列在水环境中改进纳米管分类和杂化稳定性的巨大潜力。此外，CTC3TC-(7，6)被鉴定为在所有被测样品中唯一在含血清细胞培养上清液中表现出近红外荧光强度增加的杂交种。我们的结果显示了DNA/SWCNT识别对独特的光学性质和杂化稳定性，为开发手性纯SWCNTs的应用提供了基础。
Pure-chirality single-wall carbon nanotubes (SWCNTs) that are non-covalently complexed with recognition DNA sequences exhibit unique interaction behavior and hybrid stability in aqueous environments. The complexation of DNA-wrapped SWCNTs was found to be a strong function of both the DNA sequence and SWCNT chiral structure, highlighted by the distinct coating displacement of the same recognition DNA sequence from a pair of (6,5) enantiomers by a strong surfactant. A broad range of changes were observed for different DNA/SWCNT recognition pairs with surfactant exchange including the increase in nanotube photoluminescence intensity in the near-infrared (NIR) from 1.3 to 14.7-fold and time constants deduced from DNA displacement kinetics ranging from 9 s to 230 s. A large time constant of 230 s and a relatively small 4.4-fold increase in NIR emission intensity were obtained for the CTC3TC-(7,6) hybrid highlighting the vast potential of short DNA sequences for improved nanotube sorting and hybrid stability in aqueous environments. Additionally, CTC3TC-(7,6) was identified as the only hybrid to exhibit an increase in NIR fluorescence intensity in serum-containing cell culture media among all samples tested. Our results demonstrated unique optical properties and hybrid stability of DNA/SWCNT recognition pairs, providing a foundation for developing applications of chirality-pure SWCNTs.
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影响因子：
9.5
作者：
Jena PV;Safaee MM;Heller DA;Roxbury D
通讯作者：
Roxbury D
分子拥挤诱导 DNA 包裹的碳纳米管聚集，以实现轻松的长度分级。
影响因子：
17.1
作者：
C. Khripin;Nicholas Arnold;M. Zheng
通讯作者：
M. Zheng
影响因子：
38.3
作者：
通讯作者：
--
影响因子：
23.5
作者：
Kim, Mijin;Wu, Xiaojian;Wang, YuHuang
通讯作者：
Wang, YuHuang
影响因子：
3.9
作者：
Shankar, Akshaya;Mittal, Jeetain;Jagota, Anand
通讯作者：
Jagota, Anand