Fish Consumption and Incidence of Diabetes: meta-analysis of data from 438,000 individuals in 12 independent prospective cohorts with an average 11-year follow-up.
Fish Consumption and Incidence of Diabetes: meta-analysis of data from 438,000 individuals in 12 independent prospective cohorts with an average 11-year follow-up.
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DOI：
10.2337/dc11-1869
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发表时间：
2012-04
期刊：
影响因子：
16.2
通讯作者：
He K
中科院分区：
文献类型：
--
作者：
Xun P;He K
—生态数据表明鱼类消费与糖尿病患病率呈负相关。然而，关于鱼类摄入量和糖尿病发病率的流行病学数据存在争议且尚无定论。因此，我们的目的是评估文献并定量确定鱼类消费与糖尿病风险之间的关联。 —选择了截至 2011 年 8 月在 PubMed 索引的同行评审期刊上发表的前瞻性队列研究。其他信息是通过谷歌或手动搜索相关文章的参考文献来检索的。使用随机效应模型估算了糖尿病发生的加权相对风险 (RR) 和相应的 95% CI。 — 数据库源自 9 项符合条件的研究（12 个独立队列），包括 438,214 名受试者，平均随访时间为 11.4 年。与那些从不吃鱼或每月吃鱼少于一次的人相比，每周吃鱼五次或以上的人患糖尿病的汇总 RR 为 0.99 (95% CI 0.85–1.16)（P 趋势 = 0.80）。长链 n-3 多不饱和脂肪酸摄入量也发现了类似的结果。研究地点是一个影响因素。通过结合在东方国家而非西方国家进行的研究，发现鱼类摄入量与糖尿病发病率之间存在负相关。 —本荟萃分析产生的累积证据并不支持鱼或鱼油摄入量与糖尿病发病率总体呈负相关。零关联根据研究地点（东方与西方国家）进行了修改，这可能反映了东西方饮食模式之间可能存在的差异。进一步的研究是有必要的。
—Ecological data suggest an inverse correlation between fish consumption and diabetes prevalence. However, epidemiological data on fish intake and diabetes incidence are controversial and inconclusive. Therefore, we aimed to assess the literature and determine the association between fish consumption and diabetes risk quantitatively. —Prospective cohort studies published through August 2011 in peer-reviewed journals indexed in PubMed were selected. Additional information was retrieved through Google or a hand search of the references from relevant articles. The weighted relative risk (RR) and corresponding 95% CI for incident diabetes was estimated using random-effects models. —A database was derived from nine eligible studies (12 independent cohorts), including 438,214 individuals with an average 11.4-year follow-up. Compared with those who never consumed fish or ate fish less than once per month, the pooled RR of incident diabetes was 0.99 (95% CI 0.85–1.16) for individuals who ate fish five or more times per week (P trend = 0.80). Similar results were found for long-chain n-3 polyunsaturated fatty acid intake. Study location was an effect modifier. An inverse association between fish intake and diabetes incidence was found by combining studies conducted in Eastern but not Western countries. —Accumulated evidence generated from this meta-analysis does not support an overall inverse association of fish or fish oil intake with incidence of diabetes. The null association was modified by study location (Eastern vs. Western countries), which may reflect the possible difference between Eastern and Western dietary patterns. Further studies are warranted.
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影响因子：
7.1
作者：
Brostow, Diana P.;Odegaard, Andrew O.;Pereira, Mark A.
通讯作者：
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影响因子：
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作者：
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通讯作者：
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影响因子：
7.1
作者：
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通讯作者：
Lee, I-Min
影响因子：
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作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
CAMPBELL, LV