Patterns of Body Composition Relating to Chronic Respiratory Diseases Among Adults in Four Resource-Poor Settings in Peru.
Patterns of Body Composition Relating to Chronic Respiratory Diseases Among Adults in Four Resource-Poor Settings in Peru.
复制标题
DOI:
10.1007/s00408-018-0109-7
复制
发表时间:
2018-06
期刊:
影响因子:
5
通讯作者:
CRONICAS Cohort Study
中科院分区:
文献类型:
--
作者:
Trompeter G;Grigsby MR;Miele CH;Wise RA;Gilman RH;Miranda JJ;Bernabe-Ortiz A;Checkley W;CRONICAS Cohort Study
Body composition is known to influence the development and progression of chronic respiratory diseases (CRDs). We sought to characterize the unique anthropometric phenotypes that present with asthma, chronic obstructive pulmonary disease (COPD), and chronic bronchitis across four distinct settings in Peru. We collected sociodemographic, clinical history, and spirometry data from 2,959 participants from Lima, Tumbes, and rural and urban Puno. We compared the prevalence of CRDs among different study sites and described disease phenotypes. We used single and multivariable linear regression to model the influence of CRD status on various descriptors of body composition. Overall prevalence of CRDs varied across sites with the highest prevalence of asthma in Lima (14.5%) and the highest prevalence of COPD in rural Puno (9.9%). Measures of body composition also varied across sites, with highest mean body mass index (BMI) in Lima (28.4 kg/m2) and the lowest mean BMI in rural Puno (25.2 kg/m2). Participants with COPD had the lowest mean fat mass index (10.5 kg/m2) and waist circumference (88.3 cm), whereas participants with asthma had the highest mean fat mass index (14.5 kg/m2), and waist circumference (94.8 cm). In multivariable analysis, participants with COPD had a lower waist circumference (adjusted mean −2.97 cm, 95%CI −4.62 to −1.32) when compared to non-CRD participants. Our findings provide evidence that asthma and chronic bronchitis are more likely to be associated with obesity and higher fat mass, while COPD is associated with being underweight and having less lean mass.
登录
查看更多内容
DOI:
10.1183/09031936.00080312
发表时间:
2012-12
期刊:
The European respiratory journal
影响因子:
--
作者:
Quanjer PH;Stanojevic S;Cole TJ;Baur X;Hall GL;Culver BH;Enright PL;Hankinson JL;Ip MS;Zheng J;Stocks J;ERS Global Lung Function Initiative
通讯作者:
ERS Global Lung Function Initiative
影响因子:
14.2
作者:
McLachlan, Christene R.;Poulton, Richie;Hancox, Robert J.
通讯作者:
Hancox, Robert J.
影响因子:
9.6
作者:
Chailleux, E;Laaban, JP;Veale, D
通讯作者:
Veale, D
DOI:
10.1164/ajrccm.164.8.2008109
发表时间:
2001-10-15
影响因子:
24.7
作者:
Eid, AA;Ionescu, AA;Shale, DJ
通讯作者:
Shale, DJ
DOI:
10.1186/1476-069x-13-21
发表时间:
2014-03-24
期刊:
Environmental health : a global access science source
影响因子:
--
作者:
Pollard SL;Williams DL;Breysse PN;Baron PA;Grajeda LM;Gilman RH;Miranda JJ;Checkley W;CRONICAS Cohort Study Group
通讯作者:
CRONICAS Cohort Study Group