Limited susceptibility of chickens, turkeys, and mice to pandemic (H1N1) 2009 virus.

Limited susceptibility of chickens, turkeys, and mice to pandemic (H1N1) 2009 virus.
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DOI:
10.3201/eid1604.091491
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发表时间:
2010-04
影响因子:
11.8
通讯作者:
Beer M
Beer M
中科院分区:
医学2区
文献类型:
--
作者:
Kalthoff D;Grund C;Harder TC;Lange E;Vahlenkamp TW;Mettenleiter TC;Beer M

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为了确定鸡、火鸡和小鼠对2009年H1N1大流行病毒的易感性,我们进行了接触暴露和接种实验。我们证明了鸡对感染具有抵抗力。然而,经眼经鼻接种的火鸡和经鼻接种的小鼠血清转换为阴性,没有临床感染迹象。
To determine susceptibility of chickens, turkeys, and mice to pandemic (H1N1) 2009 virus, we conducted contact exposure and inoculation experiments. We demonstrated that chickens were refractory to infection. However, oculo-oronasally inoculated turkeys and intranasally inoculated mice seroconverted without clinical signs of infection.
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