The comparison of two different mandibular positions for oral appliance therapy in patients with obstructive sleep apnea.
The comparison of two different mandibular positions for oral appliance therapy in patients with obstructive sleep apnea.
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DOI：
10.1002/cre2.650
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发表时间：
2022-12
影响因子：
1.8
通讯作者：
Masumi, Shin-Ichi
中科院分区：
文献类型：
--
作者：
Makihara, Eri;Watanabe, Takafumi;Ogusu, Hiromichi;Masumi, Shin-Ichi
口腔矫治器(OA)可以在睡眠时通过向前拉下颌来缓解上呼吸道阻塞。虽然伴随着OA的下颌大前移减少了呼吸暂停和低呼吸事件的发生，但长期使用可能会导致副作用，如牙痛、僵硬和颞下颌关节疼痛。本研究旨在评价不同下颌体位对阻塞性睡眠呼吸暂停(OSA)的治疗效果，并确定最佳治疗下颌体位。32名轻度至中度阻塞性睡眠呼吸暂停患者(17名男性和15名女性)参与了这项前瞻性研究。所有患者被随机分配到接受50%下颌前移或75%下颌前移的OA组。比较治疗前后呼吸暂停低通气指数(AHI)、呼吸暂停指数(AI)、Epworth嗜睡量表(ESS)的变化。比较两组间的治疗效果和治疗成功率。两组AHI均有明显改善，下颌前移50%组AI明显改善。两组患者的ESS评分均未见明显改善。两组治疗效果差异无统计学意义。在两组治疗有效的女性和男性比例中，女性明显高于男性。对于轻到中度阻塞性睡眠呼吸暂停的患者，建议将50%的下颌前倾作为最初的治疗下颌位。有人建议，性别差异也会影响治疗效果。
An oral appliance (OA) can alleviate upper airway obstruction by pulling the mandible forward during sleep. While a large mandibular advancement with an OA decreases the number of apnea and hypopnea events, long‐term use may cause side effects, such as toothache, stiffness, and pain in the temporomandibular joint. This study aimed to evaluate the effectiveness of different mandibular positions for obstructive sleep apnea (OSA) and determine the optimal therapeutic mandibular position. Thirty‐two patients (17 males and 15 females) with mild to moderate OSA participated in this prospective study. All patients were randomly allocated to receive a 50% mandibular advancement or a 75% mandibular advancement with an OA. The pre‐ and posttreatment apnea‐hypopnea index (AHI), apnea index (AI), and Epworth Sleepiness Scale (ESS) were compared. Treatment effectiveness and treatment success were compared between groups. AHI improved significantly in both groups, and AI improved significantly in the group with 50% mandibular advancement. No significant improvements in the ESS were observed in either group. There was no significant difference in treatment effectiveness between groups. In the proportion of females and males whose treatment was effective in the two groups, females were significantly greater than males. For patients with mild to moderate OSA, 50% mandibular advancement is recommended as the initial therapeutic mandibular position. It was suggested that gender differences also affect treatment effectiveness.
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DOI：
10.1183/16000617.0083-2019
发表时间：
2019-09-30
期刊：
European respiratory review : an official journal of the European Respiratory Society
影响因子：
--
作者：
通讯作者：
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影响因子：
10.5
作者：
Lin, Christine M.;Davidson, Terence M.;Ancoli-Israel, Sonia
通讯作者：
Ancoli-Israel, Sonia
影响因子：
9.6
作者：
HE, J;KRYGER, MH;ROTH, T
通讯作者：
ROTH, T
影响因子：
3.4
作者：
Aarab, Ghizlane;Lobbezoo, Frank;Naeije, Machiel
通讯作者：
Naeije, Machiel
DOI：
10.1164/ajrccm/147.3.624
发表时间：
1993-03-01
期刊：
AMERICAN REVIEW OF RESPIRATORY DISEASE
影响因子：
--
作者：
CLARK, GT;ARAND, D;TONG, D
通讯作者：
TONG, D