Sedentary behavior and blood pressure control among osteoarthritis initiative participants.
Sedentary behavior and blood pressure control among osteoarthritis initiative participants.
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DOI：
10.1016/j.joca.2014.07.007
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发表时间：
2014-09
影响因子：
7
通讯作者：
Dunlop, D. D.
中科院分区：
文献类型：
--
作者：
Sohn, M. -W.;Manheim, L. M.;Chang, R. W.;Greenland, P.;Hochberg, M. C.;Nevitt, M. C.;Semanik, P. A.;Dunlop, D. D.
研究骨关节炎倡议（OAI）参与者久坐行为与BP之间的关系。我们对使用加速度计测量身体活动的OAI 48个月访问参与者进行了横断面分析。根据久坐时间（每分钟活动次数<100次）的百分比，参与者被分为四个四分位数。抗高血压药物或非甾体抗炎药的使用者被排除在外。我们的主要结果是收缩压和舒张压（收缩压和舒张压）和血压升高（定义为血压≥130/85 mm Hg）。在该研究队列（N = 707）中，平均血压为121.4±15.6/74.7±9.5 mm Hg， 33%血压升高。收缩压与久坐时间的增加呈分级相关（趋势P = 0.02）。在调整了年龄、中高强度体力活动和其他人口统计学和健康因素后，久坐时间最长的四分之一组的收缩压比久坐时间最少的四分之一组高4.26毫米汞柱（95% CI, 0.69 - 7.82; p = 0.02）。久坐时间越长，血压升高的概率显著增加（趋势P = 0.046）。DBP没有明显的发现。久坐行为与收缩压升高和血压升高之间存在强烈的分级关联，与在中压体力活动中花费的时间无关。减少每天久坐的时间可能会改善血压，降低心血管风险。
To examine the association between sedentary behavior and BP among Osteoarthritis Initiative (OAI) participants. We conducted a cross-sectional analysis of the OAI 48-month visit participants whose physical activity was measured using accelerometers. Participants were classified into four quartiles according to the percentage of wear time that was sedentary (<100 activity counts per minute). Users of antihypertensive medications or NSAIDs were excluded. Our main outcomes were systolic and diastolic blood pressures (SBP and DBP) and “elevated BP” defined as BP ≥ 130/85 mm Hg. For this study cohort (N = 707), mean BP was 121.4 ± 15.6/74.7 ± 9.5 mm Hg and 33% had elevated BP. SBP had a graded association with increased sedentary time (P for trend = 0.02). The most sedentary quartile had 4.26 mm Hg higher SBP (95% CI, 0.69 – 7.82; p = 0.02) than the least sedentary quartile, adjusting for age, moderate-to-vigorous (MV) physical activity, and other demographic and health factors. The probability of having elevated BP significantly increased in higher sedentary quartiles (P for trend = 0.046). There were no significant findings for DBP. A strong graded association was demonstrated between sedentary behavior and increased SBP and elevated BP, independent of time spent in MV physical activity. Reducing daily sedentary time may lead to improvement in blood pressure and reduction in cardiovascular risk.
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影响因子：
16.2
作者：
Ekelund, Ulf;Griffin, Simon J.;Wareham, Nicholas J.
通讯作者：
Wareham, Nicholas J.
影响因子：
5.9
作者：
Bavry, Anthony A.;Khaliq, Asma;Pepine, Carl J.
通讯作者：
Pepine, Carl J.
影响因子：
120.7
作者：
Church, Timothy S.;Earnest, Conrad P.;Blair, Steven N.
通讯作者：
Blair, Steven N.
影响因子：
39.3
作者：
Healy, Genevieve N.;Matthews, Charles E.;Owen, Neville
通讯作者：
Owen, Neville
影响因子：
8.3
作者：
Grover, SA;Coupal, L;Zowall, H
通讯作者：
Zowall, H