Sustaining Independent Careers in Vision Research: Demographics and Success in Second R01 Attainment Among Clinician-Scientists from 1985 to 2019.

Sustaining Independent Careers in Vision Research: Demographics and Success in Second R01 Attainment Among Clinician-Scientists from 1985 to 2019.
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DOI:
10.1167/tvst.9.12.32
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发表时间:
2020-11
影响因子:
3
通讯作者:
Rao RC
Rao RC
中科院分区:
医学3区
文献类型:
--
作者:
Liu EA;Wang SY;Rao RC

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评估眼科和验光临床科学家在获得第二个R01(续期或新的)方面的成功,以及与此成功相关的因素,包括性别、临床专业、学位、机构和长凳研究与非长凳研究。分析了1985年至2014年首次获得国家眼科研究所(NEI)R01奖的数据(N=234),以计算第二次R01的成功率。仅包括授予眼科或验光临床科学家的R01奖项。人口统计数据来自临床医生,首次提供NEI R01资金的时间跨度从1962年到2019年(N=386)。通过进行互联网搜索,我们获得了关于第一次R01的时间跨度、第二次R01的年份、机构和项目名称的信息,这些信息包括美国国立卫生研究院(NIH)研究组合在线报告工具、支出和结果(记者)数据库,以及性别、临床专业和学位的其他衡量标准。总体而言,从1985年到2014年,62.8%的眼科或验光临床医生兼科学家获得了第二个R01;在收到第一个R01(通常是R01的长度)5年后,只有3.9%的人获得了第二个R01。研究中没有任何因素(时间队列、性别、临床专业、学位、机构或长凳研究与非长凳研究)与第二次R01的成功获得显著相关。我们发现,接受第二次R01的总体成功率为62.8%,但在第一次R01 5年后,第二次R01的成功率仅为∼4%。我们的研究为临床医生-科学家管道中的重大泄漏提供了洞察,并提出了利益相关者应该如何在临床医学和生物医学研究的交叉点支持这一重要的个人群体的问题。
To evaluate the success of ophthalmology and optometry clinician–scientists in obtaining a second R01 (renewal or new) and factors associated with this success, including gender, clinical specialty, degree, institution, and bench versus non-bench research. First-time National Eye Institute (NEI) R01 awardee data from 1985 to 2014 (N = 234) were analyzed to calculate second R01 success rates. Only R01 awards to ophthalmology or optometry clinician–scientists were included. Demographic data were obtained from clinicians with first-time NEI R01 funding spanning from 1962 to 2019 (N = 386). We obtained information regarding time span of the first R01, year of second R01, institution, and project title on the National Institutes of Health (NIH) Research Portfolio Online Reporting Tool, Expenditures and Results (RePORTER) database, and additional measures of gender, clinical specialty, and degree by performing Internet searches. Overall, from 1985 to 2014, 62.8% of ophthalmology or optometry clinician–scientists were awarded a second R01; at 5 years after receipt of the first R01 (the typical length of an R01), only 3.9% received their second R01. None of the factors examined (temporal cohort, gender, clinical specialty, degree, institution, or bench vs. non-bench research) was significantly associated with successful attainment of a second R01. We found an overall success rate of 62.8% for receiving a second R01, but 5 years after the first R01 an attainment rate for a second R01 of only ∼4%. Our study provides insight on significant leaks in the clinician–scientist pipeline and raises questions of how stakeholders should support this important group of individuals at the intersection of clinical medicine and biomedical research.
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