The Role of Platelet Concentrates in Facial Fat Grafting

The Role of Platelet Concentrates in Facial Fat Grafting
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浓缩血小板在面部脂肪移植中的作用

DOI:
10.1097/sap.0000000000001498
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发表时间:
2018-12
影响因子:
1.5
通讯作者:
Yi Chenggang
Yi Chenggang
中科院分区:
医学4区
文献类型:
--
作者:
Xiong Shaoheng;Qiu Lihong;Zhao Jianhui;Zheng Hui;Cui Dong;Su Yinjun;Yi Chenggang

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Abstract Autologous fat grafting is increasingly being used as a method for the repair of facial soft tissue defects and facial rejuvenation, given its low risk of adverse effects and high efficacy. However, the unpredictability of graft retention is a limitation of this procedure. In addition, there is no standard procedure to date for autologous fat grafting. Different methods have been developed to increase the retention of grafted fat. For instance, platelet concentrates have been used to directly deliver bioactive factors to grafted fat. Platelet concentrates also provide incidental therapeutic benefits by enhancing the persistence of fat grafted in the face via the release of growth factors and cytokines. In this review, we describe current strategies for improving the survival of facial fat grafts, mainly focusing on the application of growth factors/cytokines and platelet concentrates to fat grafting.
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