Home-Based Exercise Program Ameliorates Renal Function Decline in Patients With CKD Stage 4.

Home-Based Exercise Program Ameliorates Renal Function Decline in Patients With CKD Stage 4.
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DOI:
10.1016/j.ekir.2022.01.006
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发表时间:
2022-04
影响因子:
6
通讯作者:
Itoh, Hiroshi
Itoh, Hiroshi
中科院分区:
医学2区
文献类型:
--
作者:
Adachi, Keika;Uchiyama, Kiyotaka;Muraoka, Kaori;Nakayama, Takashin;Yasuda, Marie;Miyashita, Kazutoshi;Tokuyama, Hirobumi;Wakino, Shu;Itoh, Hiroshi

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在242例4期CKD门诊患者中,46例患者在先前的RCT中被随机分配到对照组(n = 23)和运动组(n = 23),所有这些患者均被纳入该事后分析(补充图S2)。研究受试者在基线(运动干预开始时)的临床特征,包括eGFR斜率、运动前阶段体重随体重指数的变化(D)、血压(BP)和心率总结见表1。在运动前、运动中期和运动后期间,分别进行7(6-9)、4(4-5)和4(3-5)次eGFR斜率计算的eGFR测量。对照组和运动组在这些临床参数方面没有显著差异。此外,基线体力活动评估使用
RESULTSPatients and Baseline Characteristics Among 242 outpatients with stage 4 CKD, 46 patients were randomly assigned to the control group (n ž 23) and the exercise group (n ž 23) in the previous RCT, and all of these patients were included in this post hoc analysis (Supplementary Figure S2). The clinical characteristics of study participants at baseline (at the start of exercise intervention), including eGFR slope, changes (D) in body weight with body mass index, blood pressure (BP), and heart rate during the pre-exercise period, are summarized in Table 1. eGFR measurements for eGFR slope calculation were performed 7 (6–9), 4 (4–5), and 4 (3–5) times during the preexercise, midexercise, and postexercise periods, respectively. The control and exercise groups had no significant differences in these clinical parameters. Moreover, baseline physical activity evaluated using the
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