UniProt: the universal protein knowledgebase in 2021.
UniProt: the universal protein knowledgebase in 2021.
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DOI：
10.1093/nar/gkaa1100
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发表时间：
2021-01-08
影响因子：
14.9
通讯作者：
UniProt Consortium
中科院分区：
文献类型：
--
作者：
UniProt Consortium
UniProt知识库的目的是为用户提供一个全面的，高质量的和免费访问的一套蛋白质序列注释功能信息。在本文中，我们描述了我们在过去两年中对资源所做的重大更新。UniProtKB中的序列数量已经上升到大约1.9亿，尽管在蛋白质组水平上持续努力减少序列冗余。我们采用了新的方法来评估蛋白质组的完整性和质量。我们继续从文献中提取详细的注释，以添加到已审查的条目中，并在未经审查的条目中补充由自动系统（如新实现的基于关联规则的注释器（ARBA））提供的注释。我们开发了一个基于学分的出版物提交界面，允许社区为UniProt条目贡献出版物和注释。我们描述了UniProtKB如何通过专家整理相关条目来应对COVID-19大流行，这些条目通过专门的门户网站迅速提供给研究界。UniProt资源可以在CC-BY（4.0）许可证下通过https://www.uniprot.org/网站获得。
The aim of the UniProt Knowledgebase is to provide users with a comprehensive, high-quality and freely accessible set of protein sequences annotated with functional information. In this article, we describe significant updates that we have made over the last two years to the resource. The number of sequences in UniProtKB has risen to approximately 190 million, despite continued work to reduce sequence redundancy at the proteome level. We have adopted new methods of assessing proteome completeness and quality. We continue to extract detailed annotations from the literature to add to reviewed entries and supplement these in unreviewed entries with annotations provided by automated systems such as the newly implemented Association-Rule-Based Annotator (ARBA). We have developed a credit-based publication submission interface to allow the community to contribute publications and annotations to UniProt entries. We describe how UniProtKB responded to the COVID-19 pandemic through expert curation of relevant entries that were rapidly made available to the research community through a dedicated portal. UniProt resources are available under a CC-BY (4.0) license via the web at https://www.uniprot.org/.
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DOI：
10.3233/jad-200206
发表时间：
2020
期刊：
Journal of Alzheimer's disease : JAD
影响因子：
--
作者：
Breuza L;Arighi CN;Argoud-Puy G;Casals-Casas C;Estreicher A;Famiglietti ML;Georghiou G;Gos A;Gruaz-Gumowski N;Hinz U;Hyka-Nouspikel N;Kramarz B;Lovering RC;Lussi Y;Magrane M;Masson P;Perfetto L;Poux S;Rodriguez-Lopez M;Stoeckert C;Sundaram S;Wang LS;Wu E;Orchard S;IMEx Consortium, UniProt Consortium
通讯作者：
IMEx Consortium, UniProt Consortium
影响因子：
14.9
作者：
Mitchell AL;Attwood TK;Babbitt PC;Blum M;Bork P;Bridge A;Brown SD;Chang HY;El-Gebali S;Fraser MI;Gough J;Haft DR;Huang H;Letunic I;Lopez R;Luciani A;Madeira F;Marchler-Bauer A;Mi H;Natale DA;Necci M;Nuka G;Orengo C;Pandurangan AP;Paysan-Lafosse T;Pesseat S;Potter SC;Qureshi MA;Rawlings ND;Redaschi N;Richardson LJ;Rivoire C;Salazar GA;Sangrador-Vegas A;Sigrist CJA;Sillitoe I;Sutton GG;Thanki N;Thomas PD;Tosatto SCE;Yong SY;Finn RD
通讯作者：
Finn RD
影响因子：
14.9
作者：
The Gene Ontology Consortium
通讯作者：
The Gene Ontology Consortium
影响因子：
14.9
作者：
Moriya Y;Kawano S;Okuda S;Watanabe Y;Matsumoto M;Takami T;Kobayashi D;Yamanouchi Y;Araki N;Yoshizawa AC;Tabata T;Iwasaki M;Sugiyama N;Tanaka S;Goto S;Ishihama Y
通讯作者：
Ishihama Y
DOI：
10.1093/database/baaa006
发表时间：
2020-03-17
影响因子：
5.8
作者：
Arnaboldi, Valerio;Raciti, Daniela;Sternberg, Paul W.
通讯作者：
Sternberg, Paul W.