Radiolysis of carbamazepine by electron beam: Roles of transient reactive species and biotoxicity of final reaction solutions on rotifer Philodina sp.
Radiolysis of carbamazepine by electron beam: Roles of transient reactive species and biotoxicity of final reaction solutions on rotifer Philodina sp.
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电子束辐射解卡马西平：瞬时活性物质的作用和最终反应溶液对轮虫 Philodina sp 的生物毒性。
DOI：
10.1016/j.scitotenv.2019.135013
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发表时间：
2019-11
影响因子：
9.8
通讯作者：
Wang Zhongying
中科院分区：
文献类型：
--
作者：
Zheng Ming;Bao Yangyang;Huang Zhonglian;Qiu Wenhui;Xu Gang;Wang Zhongying
电子束（EB）已被证明是一种有效的降解精神药物卡马西平（CBZ）的高级氧化还原过程（AORP）；然而，最终反应溶液的降解机理和对水生微生物的毒性还有待进一步研究。在本研究中，CBZ最终被EB处理降解甚至矿化，其中CBZ的降解遵循准一级动力学，R2> 0.98。酸性条件、附加氧化剂（2.5 mmol L−1H2O2）的存在以及O2/空气饱和条件提高了CBZ的降解效率，以及辐射化学产率（g值定义为辐照过程的效率）。在0.956和3.17 kGy剂量下，测定了不同条件下EB引起的瞬时反应种（TRS）浓度，CBZ降解的表观量子产率依次为自由基dotOH >自由基do >eaq−。然而，这些物种对CBZ降解的贡献顺序为自由基dotOH >eaq−>自由基do，因为自由基do的产生量很少。CBZ降解中间体、短链脂肪酸（SCFAs）和总有机碳的变化表明，CBZ可以通过EB过程逐渐矿化为CO2/CO32−、H2O和NH3/NH4+。此外，在5-kGy处理的反应溶液中培养5天后，轮虫的存活率很高，这表明EB可以作为一种安全的orp来矿化溶液中的CBZ。这些发现为EB是一种有效的去除水溶液中精神药物的主动脉主动脉瓣提供了科学依据，为今后的修复研究奠定了基础。
Electron beam (EB) has proven to be an effective advanced oxidation reduction process (AORP) to degrade the psychiatric drug carbamazepine (CBZ); however, the degradation mechanism and the toxicity of the final reaction solutions to aquatic microorganisms needed further investigation. In this study, CBZ was eventually degraded and even mineralized by EB treatment, where the degradation of CBZ followed the pseudo-first-order kinetics with R2> 0.98. Acidic conditions, presence of an additional oxidant (2.5 mmol L−1H2O2), and O2/air-saturated conditions improved the degradation efficiency of CBZ, as well as the radiation chemical yield (G-value defined as the efficiency of the irradiation process). Concentrations of transient reactive species (TRS) caused by EB were quantified under different conditions at doses of 0.956 and 3.17 kGy, and the apparent quantum yield of CBZ degradation was in the order ofradical dotOH >radical dotH >eaq−. However, the contribution of these species to CBZ degradation was in the order ofradical dotOH >eaq−>radical dotH due to the generation of only a small amount ofradical dotH. Findings regarding the changes of in CBZ degradation intermediates, short-chain fatty acids (SCFAs), and total organic carbon showed that CBZ can gradually be mineralized into CO2/CO32−, H2O, and NH3/NH4+by the EB process. Additionally, an excellent rotifer survival rate after 5-day culturing in the reaction solutions resulting from 5-kGy treatment indicated that EB can be a safe AORP to mineralize CBZ in solution. These findings provide scientific proof for the EB being an effective AORP for removal of psychiatric drugs from aqueous solutions, laying the foundation for future remediation research.
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影响因子：
4.1
作者：
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通讯作者：
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