Diffusion tensor imaging of normal brain development.

Diffusion tensor imaging of normal brain development.
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DOI:
10.1007/s00247-012-2496-x
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发表时间:
2013-01
影响因子:
2.3
通讯作者:
Mori S
Mori S
中科院分区:
医学3区
文献类型:
--
作者:
Yoshida S;Oishi K;Faria AV;Mori S

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扩散张量成像(DTI)是一种可以测量脑组织宏观结构组织的MRI技术。DTI已被证明可以提供有关大脑微观结构变化的信息,与基于弛豫的MRI互补。在儿科人群中,DTI能够定量观察白色物质结构的成熟过程。它描绘发育阶段各种脑结构的能力使其成为表征发育中大脑正常和异常解剖结构的有效工具。本文将重点介绍小儿DTI的优点以及常见的技术缺陷。此外,各种DTI衍生的参数和与这些参数相关的正常大脑发育变化的图像量化策略进行了讨论。
Diffusion tensor imaging (DTI) is an MRI technique that can measure the macroscopic structural organization in brain tissues. DTI has been shown to provide information complementary to relaxation-based MRI about the changes in the brain's microstructure. In the pediatric population, DTI enables quantitative observation of the maturation process of white matter structures. Its ability to delineate various brain structures during developmental stages makes it an effective tool with which to characterize both the normal and abnormal anatomy of the developing brain. This review will highlight the advantages, as well as the common technical pitfalls of pediatric DTI. In addition, image quantification strategies for various DTI-derived parameters and the normal brain developmental changes associated with these parameters are discussed.
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