The changing vaccine landscape: rates of COVID-19 vaccine acceptance and hesitancy in young adults during vaccine rollout.
The changing vaccine landscape: rates of COVID-19 vaccine acceptance and hesitancy in young adults during vaccine rollout.
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DOI：
10.1177/17579139221094750
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发表时间：
2023-07
影响因子：
5.8
通讯作者：
Vedhara, K.
中科院分区：
文献类型：
--
作者：
Knight, H.;Jia, R.;Ayling, K.;Blake, H.;Morling, J. R.;Villalon, A. M.;Corner, J.;Denning, C.;Ball, J.;Bolton, K.;Figueredo, G.;Morris, D.;Tighe, P.;Vedhara, K.
疫苗的开发和推广为保护人群免受SARS-CoV-2 （COVID-19）病毒的侵害提供了最佳机会。然而，在英国，对疫苗的犹豫可能会阻碍疫苗的成功吸收，特别是在年轻人中，他们表现出最高的犹豫率。这项前瞻性研究探讨了年轻人对COVID-19疫苗的犹豫态度，以及这些态度背后的原因在英国疫苗推广的初始阶段是否发生了变化。在三个时间点（2020年10月、2021年2月和2021年3月）从英国大学生队列中收集了疫苗接种意向的数据。这项在线调查包括关于接种疫苗意愿的项目，以及关于这一意愿背后原因的自由文本回复。科克伦的Q测试考察了犹豫率和接受率随时间的变化，并对自由文本的回答进行了主题分析。在基线时，893名学生提供了数据，476名参与者完成了所有三个时间点。犹豫随着时间的推移而下降，29.4%的参与者在基线时表现出犹豫，在第二波和第三波时分别降至9.1%和5.9%。对于那些愿意接受疫苗的人来说，最普遍认可的主题是针对COVID-19的自我保护和亲社会原因，包括保护人群或非特定人群，以及结束大流行/恢复正常生活。最普遍认可的犹豫主题与对疫苗的“信心”和潜在的个人风险有关，包括测试/科学证据不足、对副作用和长期影响的担忧。这些原因在第二波和第三波中都得到了最普遍的认可。虽然随着时间的推移，人们的犹豫有所减少，但疫苗接受和犹豫背后的主要原因仍然是一致的。犹豫背后的原因与一般公众的原因一致，为使用综合干预措施提供了支持。亲社会的原因往往是疫苗接受的基础，因此针对这些因素的群体特定干预可能是有益的。
Development and rollout of vaccines offers the best opportunity for population protection against the SARS-CoV-2 (COVID-19) virus. However, hesitancy towards the vaccines might impede successful uptake in the United Kingdom, particularly in young adults who demonstrate the highest rates of hesitancy. This prospective study explored COVID-19 vaccine hesitancy in young adults and whether the reasons behind these attitudes changed during the initial stages of the United Kingdom’s vaccine rollout. Data on vaccination intention were collected from a British university student cohort at three time points: October 2020, February 2021, and March 2021. This online survey included items on intention to receive a vaccine and a free-text response for the reasons behind this intention. Cochran’s Q tests examined changes in rates of hesitancy and acceptance over time and free-text responses were analysed thematically. At baseline, 893 students provided data, with 476 participants completing all three time points. Hesitancy declined over time, with 29.4% of participants expressing hesitancy at baseline, reducing to 9.1% at wave 2 and 5.9% at wave 3. The most commonly endorsed themes for those willing to accept a vaccine were self-protection against COVID-19 and pro-social reasons, including protecting the population or unspecific others, and ending the pandemic/returning to normal life. The most commonly endorsed hesitancy themes related to ‘confidence’ in the vaccines and potential personal risk, including insufficient testing/scientific evidence, concern about side effects, and long-term effects. These reasons remained the most commonly endorsed at both waves 2 and 3. While a decline in hesitancy was observed over time, the key reasons behind both vaccine acceptance and hesitancy remained consistent. Reasons behind hesitancy aligned with those of the general public, providing support for the use of generalist interventions. Pro-social reasons frequently underpinned vaccine acceptance, so cohort-specific interventions targeting those factors may be of benefit.
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DOI：
10.1016/j.bbi.2021.03.008
发表时间：
2021-05
期刊：
Brain, behavior, and immunity
影响因子：
--
作者：
Robertson E;Reeve KS;Niedzwiedz CL;Moore J;Blake M;Green M;Katikireddi SV;Benzeval MJ
通讯作者：
Benzeval MJ
影响因子：
1.3
作者：
Prybutok, Gayle;Ryan, Sherry
通讯作者：
Ryan, Sherry
影响因子：
6.2
作者：
Lang, Pierre Olivier;Aspinall, Richard
通讯作者：
Aspinall, Richard
DOI：
10.1016/s0140-6736(20)31558-0
发表时间：
2020-09-26
期刊：
Lancet (London, England)
影响因子：
--
作者：
de Figueiredo A;Simas C;Karafillakis E;Paterson P;Larson HJ
通讯作者：
Larson HJ
影响因子：
5.2
作者：
Knight H;Jia R;Ayling K;Bradbury K;Baker K;Chalder T;Morling JR;Durrant L;Avery T;Ball JK;Barker C;Bennett R;McKeever T;Vedhara K
通讯作者：
Vedhara K