Structural plasticity of the ventral stream and aphasia recovery.
Structural plasticity of the ventral stream and aphasia recovery.
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DOI：
10.1002/ana.24983
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发表时间：
2017-07
影响因子：
11.2
通讯作者：
Bonilha L
中科院分区：
文献类型：
--
作者：
McKinnon ET;Fridriksson J;Glenn GR;Jensen JH;Helpern JA;Basilakos A;Rorden C;Shih AY;Spampinato MV;Bonilha L
脑卒中后失语症患者的言语恢复可能需要重新强化残余的语言网络。八名慢性失语症患者接受了为期三周的强化言语治疗，治疗前后进行了标准化的命名测试和脑MRI。基于峰度的弥散张量纤维束成像被用来测量沿着下纵束（ILF）段的平均峰度（MK）。治疗相关的语义错误而非音位错误的数量减少与ILF MK的加强（重新规范化）相关（r=-0.90，P<0.05校正），表明言语恢复与残余语言网络的语言特异性成分的结构可塑性有关。
Re-strengthening of the residual language network is likely crucial for speech recovery in post-stroke aphasia. Eight participants with chronic aphasia received intensive speech therapy for three weeks, with standardized naming tests and brain MRIs before and after therapy. Kurtosis-based diffusion tensor tractography was used to measure mean kurtosis (MK) along a segment of the inferior longitudinal fasciculus (ILF). Therapy related reduction in the number of semantic but not phonemic errors was associated with strengthening (renormalization) of ILF MK (r=-0.90, P<0.05 corrected), suggesting that speech recovery is related to structural plasticity of linguistic specific components of the residual language network.
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影响因子：
2.9
作者：
Jensen, Jens H.;Helpern, Joseph A.
通讯作者：
Helpern, Joseph A.
影响因子：
4.4
作者：
Latt, Jimmy;Nilsson, Markus;Wirestam, Ronnie;Stahlberg, Freddy;Karlsson, Nils;Johansson, Mikael;Sundgren, Pia C.;van Westen, Danielle
通讯作者：
van Westen, Danielle
影响因子：
4.4
作者：
Yang, Alicia W.;Jensen, Jens H.;Helpern, Joseph A.
通讯作者：
Helpern, Joseph A.
影响因子：
3.5
作者：
Glenn, G. R.;Kuo, L. -W.;Jensen, J. H.
通讯作者：
Jensen, J. H.
DOI：
10.1044/1058-0360(2012/11-0089
发表时间：
2012-05-01
影响因子：
2.6
作者：
Walker, Grant M.;Schwartz, Myrna F.
通讯作者：
Schwartz, Myrna F.