Regional values of diffusional kurtosis estimates in the healthy brain.
Regional values of diffusional kurtosis estimates in the healthy brain.
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DOI：
10.1002/jmri.23857
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发表时间：
2013-03
影响因子：
4.4
通讯作者：
van Westen, Danielle
中科院分区：
文献类型：
--
作者：
Latt, Jimmy;Nilsson, Markus;Wirestam, Ronnie;Stahlberg, Freddy;Karlsson, Nils;Johansson, Mikael;Sundgren, Pia C.;van Westen, Danielle
提供健康大脑中解剖学定义区域的弥散峰度估计值，并列出这些沿着先前报告的病理学值。36名志愿者（平均年龄= 33.1岁;范围：19-64岁）接受了弥散峰度成像。在26个解剖结构中测定平均峰度（MK）、径向峰度（RK）、平均扩散率（MD）、径向扩散率（RD）和各向异性分数（FA）。评估了年龄依赖性的参数估计值。胼胝体压部的MK为1.38，尾状头为0.66，MD为0.68 ~ 0.62 μm2/ms，FA为0.87 ~ 0.29。MK与FA呈强正相关，RK与RD呈强负相关。参数估计显示在某些地区的年龄相关性，也平均MK和RK的所有WM和所有GM地区，分别与年龄呈负相关。DKI参数估计值MK和RK因解剖部位而异，并随合并WM和GM数据中的年龄而异。内囊、胼胝体和丘脑的MK估计值与先前的研究一致。正常脑组织MK、RK值范围与病变脑组织重叠。J.磁共振Imaging 2013;37：610-618.© 2012 Wiley Periodicals，Inc.
To provide estimates of the diffusional kurtosis in the healthy brain in anatomically defined areas and list these along previously reported values in pathologies. Thirty-six volunteers (mean age = 33.1 years; range, 19–64 years) underwent diffusional kurtosis imaging. Mean kurtosis (MK), radial kurtosis (RK), mean diffusivity (MD), radial diffusivity (RD), and fractional anisotropy (FA) were determined in 26 anatomical structures. Parameter estimates were assessed regarding age dependence. MK varied from 1.38 in the splenium of the corpus callosum to 0.66 in the caudate head, MD varied from 0.68 to 0.62 μm2/ms and FA from 0.87 to 0.29. MK, and FA showed a strong positive correlation, RK and RD a strong negative correlation. Parameter estimates showed age correlation in some regions; also the average MK and RK for all WM and all GM areas, respectively, were negatively correlated with age. DKI parameter estimates MK and RK varied depending on the anatomical region and varied with age in pooled WM and GM data. MK estimates in the internal capsule, corpus callosum, and thalamus were consistent with previous studies. The range of values of MK and RK in healthy brain overlapped with that in pathologies. J. Magn. Reson. Imaging 2013;37:610–618. © 2012 Wiley Periodicals, Inc.
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影响因子：
2.9
作者：
Jensen, Jens H.;Helpern, Joseph A.
通讯作者：
Helpern, Joseph A.
影响因子：
4.4
作者：
Helpern, Joseph A.;Adisetiyo, Vitria;Falangola, Maria F.;Hu, Caixia;Di Martino, Adriana;Williams, Kathleen;Castellanos, Francisco X.;Jensen, Jens H.
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4.4
作者：
Falangola, Maria F.;Jensen, Jens H.;Babb, James S.;Hu, Caixia;Castellanos, Francisco X.;Di Martino, Adriana;Ferris, Steven H.;Helpern, Joseph A.
通讯作者：
Helpern, Joseph A.
影响因子：
5.7
作者：
Zhu, Tong;Hu, Rui;Qiu, Xing;Taylor, Michael;Tso, Yuen;Yiannoutsos, Constantin;Navia, Bradford;Mori, Susumu;Ekholm, Sven;Schifitto, Giovanni;Zhong, Jianhui
通讯作者：
Zhong, Jianhui