Gestational age and hospital admission costs from birth to childhood: a population-based record linkage study in England.

Gestational age and hospital admission costs from birth to childhood: a population-based record linkage study in England.
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DOI:
10.1136/archdischild-2022-324763
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发表时间:
2023-09
期刊:
Archives of disease in childhood. Fetal and neonatal edition
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研究出生时胎龄与从出生到8岁的住院费用之间的关系。英国基于人群的记录联系队列研究。英国英格兰的国民健康服务(NHS)医院。2005年1月1日至2006年12月31日期间,英格兰国民保健服务医院的1 018 136例活产单胎婴儿。从出生到8岁的住院费用,按出生时胎龄(<28、28-29、30-31、32、33、34、35、36、37、38、39、40、41和42周)估计。出生入院和随后的住院费用随着出生时胎龄的增加而下降。胎龄组之间住院费用的差异随着年龄的增加而减少,特别是在出生后的前2年。极早产儿(<28周)和极早产(28-31周)的平均住院费用仍然较高(699英镑(95%CI 419英镑至919英镑)<28周; 434英镑(95%CI 305英镑至563英镑),28-31周),与40周出生的儿童(109英镑,95%CI 104英镑至114英镑)相比。极早产儿的8年累计住院费用最高(80 559英镑(95% CI 79 238英镑至82 019英镑)),其中大部分发生在出生后的第一年(71 997英镑(95% CI 70 866英镑至73 097英镑))。出生时的胎龄和住院费用之间的联系一直持续到儿童中期。研究结果为未来的经济评估提供了有用的成本资源,重点是早产儿的预防和治疗策略。
To examine the association between gestational age at birth and hospital admission costs from birth to 8 years of age. Population-based, record linkage, cohort study in England. National Health Service (NHS) hospitals in England, UK. 1 018 136 live, singleton births in NHS hospitals in England between 1 January 2005 and 31 December 2006. Hospital admission costs from birth to age 8 years, estimated by gestational age at birth (<28, 28–29, 30–31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41 and 42 weeks). Both birth admission and subsequent admission hospital costs decreased with increasing gestational age at birth. Differences in hospital admission costs between gestational age groups diminished with increasing age, particularly after the first 2 years following birth. Children born extremely preterm (<28 weeks) and very preterm (28–31 weeks) still had higher average hospital admission costs (£699 (95% CI £419 to £919) for <28 weeks; £434 (95% CI £305 to £563) for 28–31 weeks) during the eighth year of life compared with children born at 40 weeks (£109, 95% CI £104 to £114). Children born extremely preterm had the highest 8-year cumulative hospital admission costs per child (£80 559 (95% CI £79 238 to £82 019)), a large proportion of which was incurred during the first year after birth (£71 997 (95% CI £70 866 to £73 097)). The association between gestational age at birth and hospital admission costs persists into mid-childhood. The study results provide a useful costing resource for future economic evaluations focusing on preventive and treatment strategies for babies born preterm.
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