The yeast response to heat shock

The yeast response to heat shock
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酵母对热休克的反应

DOI:
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发表时间:
2003
期刊:
影响因子:
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通讯作者:
K. Morano
K. Morano
中科院分区:
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文献类型:
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作者:
A. Trott;K. Morano

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Yeast respond to cytotoxic thermal stress via the activation of a gene expression program governed by dedicated stress-responsive transcription factors. Rapid synthesis of heat shock proteins serves to protect proteins and cellular functions from the deleterious effects of heat. We review the intricacies of heat shock gene expression, with emphasis on the transcription factor Hsf1p. New investigations into heat shock protein functions within the cell are discussed, focusing on the Hsp90 chaperone system and the role of chaperones in prion formation and propagation. We close with new insights into the links between stress responses and aging.
DOI: --
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