Dietary meat and fat intake and prevalence of rhinoconjunctivitis in pregnant Japanese women: baseline data from the Kyushu Okinawa Maternal and Child Health Study.
Dietary meat and fat intake and prevalence of rhinoconjunctivitis in pregnant Japanese women: baseline data from the Kyushu Okinawa Maternal and Child Health Study.
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DOI：
10.1186/1475-2891-11-19
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发表时间：
2012-03-27
影响因子：
5.4
通讯作者：
Arakawa M
中科院分区：
文献类型：
--
作者：
Miyake Y;Tanaka K;Okubo H;Sasaki S;Arakawa M
膳食脂肪对促炎和免疫途径产生许多复杂的影响。一些流行病学研究已经检查了脂肪酸和/或高脂肪食物的摄入与过敏性鼻炎之间的关系，但提供了相互矛盾的结果。目前的横断面研究调查了日本的这种关系。研究对象为1745名孕妇。鼻结膜炎的定义是基于国际儿童哮喘和过敏研究的标准。饮食因素的信息收集使用一个有效的自我管理的饮食史问卷。按年龄作了调整;妊娠;居住地区;年长的兄弟姐妹人数;子女人数;吸烟;家庭和工作场所的二手烟暴露;哮喘、特应性湿疹和过敏性鼻炎的家族史;家庭收入;教育;以及身体质量指数。过去12个月内鼻结膜炎的患病率为25.9%。较高的肉类摄入量与鼻结膜炎患病率的增加显著相关：极端四分位数之间的校正比值比为1.71（95%置信区间：1.25-2.35，趋势P = 0.002）。在鱼类摄入量和鼻结膜炎之间没有发现可测量的关联。总脂肪、饱和脂肪酸、单不饱和脂肪酸、n-3多不饱和脂肪酸、α-亚麻酸、二十碳五烯酸、二十二碳六烯酸、n-6多不饱和脂肪酸、亚油酸、花生四烯酸和胆固醇的摄入量以及n-3与n-6多不饱和脂肪酸的摄入量之比与鼻结膜炎的患病率无明显相关性。目前的研究结果表明，肉类摄入量可能与日本年轻成年女性鼻结膜炎的患病率呈正相关。
Dietary fat exerts numerous complex effects on proinflammatory and immunologic pathways. Several epidemiological studies have examined the relationships between intake of fatty acids and/or foods high in fat and allergic rhinitis, but have provided conflicting findings. The current cross-sectional study investigated such relationships in Japan. Study subjects were 1745 pregnant women. The definition of rhinoconjunctivitis was based on criteria from the International Study of Asthma and Allergies in Childhood. Information on dietary factors was collected using a validated self-administered diet history questionnaire. Adjustment was made for age; gestation; region of residence; number of older siblings; number of children; smoking; secondhand smoke exposure at home and at work; family history of asthma, atopic eczema, and allergic rhinitis; household income; education; and body mass index. The prevalence of rhinoconjunctivitis in the past 12 months was 25.9%. Higher meat intake was significantly associated with an increased prevalence of rhinoconjunctivitis: the adjusted odds ratio between extreme quartiles was 1.71 (95% confidence interval: 1.25-2.35, P for trend = 0.002). No measurable association was found between fish intake and rhinoconjunctivitis. Intake of total fat, saturated fatty acids, monounsaturated fatty acids, n-3 polyunsaturated fatty acids, α-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, n-6 polyunsaturated fatty acids, linoleic acid, arachidonic acid, and cholesterol and the ratio of n-3 to n-6 polyunsaturated fatty acid intake were not evidently related to the prevalence of rhinoconjunctivitis. The current results suggest that meat intake may be positively associated with the prevalence of rhinoconjunctivitis in young adult Japanese women.
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影响因子：
3.1
作者：
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通讯作者：
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影响因子：
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