Urine-Derived Stem Cells: The Present and the Future.

Urine-Derived Stem Cells: The Present and the Future.
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尿液干细胞:现在和未来

DOI:
10.1155/2017/4378947
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发表时间:
2017
影响因子:
4.3
通讯作者:
Zhou J
Zhou J
中科院分区:
医学3区
文献类型:
--
作者:
Ji X;Wang M;Chen F;Zhou J

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干细胞研究为改善人类医疗保健提供了有希望的策略。尿源性干细胞作为一种无创获取、易于培养、成本相对较低的细胞资源,具有特殊的优势。它们的增殖能力和分化潜力已被广泛研究,并在过去十年中被重新编程以模拟疾病。本文就尿源性干细胞在再生医学和疾病建模方面的广泛应用以及目前面临的挑战等方面的最新研究进展进行综述。本文将重点介绍尿源性干细胞的潜在应用,并为今后进一步研究提供可能的方向。
Stem cell research provides promising strategies in improving healthcare for human beings. As a noninvasively obtained and easy-to-culture cell resource with relatively low expense, urine-derived stem cells have special advantages. They have been extensively studied on its proliferation ability and differentiation potential and were being reprogrammed to model diseases during the last decade. In this review, we intend to summarize the latest progress on the research of urine-derived stem cells for its broad application mainly in regenerative medicine and disease modeling, as well as in what is challenging currently. This minireview will highlight the potential application of urine-derived stem cells and provides possible direction of further research in the future.
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