Brain dynamics of (a)typical reading development-a review of longitudinal studies.
Brain dynamics of (a)typical reading development-a review of longitudinal studies.
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(a)典型阅读发展的脑动力学——纵向研究回顾。
DOI：
10.1038/s41539-020-00081-5
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发表时间：
2021-02-01
影响因子：
4.2
通讯作者：
Jednoróg K
中科院分区：
文献类型：
--
作者：
Chyl K;Fraga-González G;Brem S;Jednoróg K
扫盲发展是一个过程，而不是单一事件，因此应在多个时间点进行研究。采用神经成像方法的纵向设计提供了识别与阅读发展相关的神经变化的可能性，并揭示了阅读困难的早期标志。这篇综述的核心是对典型和非典型阅读发展的纵向神经成像研究结果的总结。这项研究侧重于用单一的神经成像时间点预测阅读收益，补充了这篇综述。来自结构研究的证据表明，阅读发展导致左半球语言区域结构完整性和功能专门化程度的提高。在有阅读障碍风险的儿童中，这些神经束中一些受损的完整性可能会被同源右脑脑束更高的解剖连接所补偿。在功能方面，语音和视听整合区域的激活以及腹侧枕颞皮质(VOT)对印刷的敏感性增强似乎是成功阅读习得的相关神经发育标志。阅读训练开始时的非典型VOT反应和婴儿听觉脑电位被认为是阅读障碍的神经成像预测指标，可以补充行为测量。除了这些洞察力，关于阅读和阅读障碍的纵向神经成像研究仍然相对较少，样本量小引发了对结果可靠性的合理担忧。这篇综述讨论了这些研究的挑战，并提出了改进这一研究领域的建议。未来需要进行更大样本量的纵向研究，以提高我们对典型和非典型阅读神经发育的了解。
Literacy development is a process rather than a single event and thus should be studied at multiple time points. A longitudinal design employing neuroimaging methods offers the possibility to identify neural changes associated with reading development, and to reveal early markers of dyslexia. The core of this review is a summary of findings from longitudinal neuroimaging studies on typical and atypical reading development. Studies focused on the prediction of reading gains with a single neuroimaging time point complement this review. Evidence from structural studies suggests that reading development results in increased structural integrity and functional specialization of left-hemispheric language areas. Compromised integrity of some of these tracts in children at risk for dyslexia might be compensated by higher anatomical connectivity in the homologous right hemisphere tracts. Regarding function, activation in phonological and audiovisual integration areas and growing sensitivity to print in the ventral occipito-temporal cortex (vOT) seem to be relevant neurodevelopmental markers of successful reading acquisition. Atypical vOT responses at the beginning of reading training and infant auditory brain potentials have been proposed as neuroimaging predictors of dyslexia that can complement behavioral measures. Besides these insights, longitudinal neuroimaging studies on reading and dyslexia are still relatively scarce and small sample sizes raise legitimate concerns about the reliability of the results. This review discusses the challenges of these studies and provides recommendations to improve this research area. Future longitudinal research with larger sample sizes are needed to improve our knowledge of typical and atypical reading neurodevelopment.
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影响因子：
4.8
作者：
Brennan, Christine;Cao, Fan;Pedroarena-Leal, Nicole;McNorgan, Chris;Booth, James R.
通讯作者：
Booth, James R.
影响因子：
5.7
作者：
Ducharme S;Albaugh MD;Nguyen TV;Hudziak JJ;Mateos-Pérez JM;Labbe A;Evans AC;Karama S;Brain Development Cooperative Group
通讯作者：
Brain Development Cooperative Group
神经影像学中脑部疾病的单受试者预测：前景和陷阱
影响因子：
5.7
作者：
Arbabshirani MR;Plis S;Sui J;Calhoun VD
通讯作者：
Calhoun VD
DOI：
10.1038/nrn.2018.1
发表时间：
2018-02-16
期刊：
Nature reviews. Neuroscience
影响因子：
--
作者：
Gilmore JH;Knickmeyer RC;Gao W
通讯作者：
Gao W
影响因子：
3.6
作者：
De Vos, Astrid;Vanvooren, Sophie;Wouters, Jan
通讯作者：
Wouters, Jan