Effects of Pregnancy and Nutritional Status on Alcohol Metabolism
Effects of Pregnancy and Nutritional Status on Alcohol Metabolism
复制标题
怀孕和营养状况对酒精代谢的影响
DOI：
--
复制
发表时间：
2007
期刊：
影响因子：
--
通讯作者：
T. Badger
中科院分区：
文献类型：
--
作者：
K. Shankar;M. Ronis;T. Badger
Metabolism of alcohol (i.e., ethanol) is regulated by genetic and environmental factors as well as physiologic state. For a given alcohol intake, the rate of alcohol clearance, which ultimately determines tissue ethanol concentrations, may be the most significant risk factor for many of the detrimental effects of alcohol. Faster ethanol clearance would help minimize target tissue concentrations, and in pregnant women, mitigate fetal alcohol exposure. Much remains to be known about the effects of the altered endocrine milieu of pregnancy on alcohol metabolism and clearance in the mother. Research has shown that among pregnant rats allowed unrestricted access to alcohol and those fed alcohol containing liquid diets under experimental conditions via a feeding tube (total enteral nutrition [TEN]), urine ethanol concentrations (and thus blood and tissue ethanol concentrations) are lower in pregnant rats compared with non-pregnant females given the same dose of ethanol. Maternal nutritional status also is an important determinant of fetal alcohol toxicity. Research using the TEN system has demonstrated that alcohol-induced fetal growth retardation is potentiated by undernutrition in part via impaired alcohol metabolism and clearance.
登录
查看更多内容
乙醇和母亲营养状况对胎儿发育的影响。
DOI：
10.1111/j.1530-0277.1985.tb05049.x
发表时间：
1985
期刊：
Alcoholism, clinical and experimental research
影响因子：
--
作者：
Weinberg,J
通讯作者：
Weinberg,J
产前乙醇暴露对胎儿钙代谢的影响。
DOI：
--
发表时间：
1997
期刊：
Alcoholism, clinical and experimental research
影响因子：
--
作者：
Keiver,K;Ellis,L;Anzarut,A;Weinberg,J
通讯作者：
Weinberg,J
DOI：
10.1111/j.1530-0277.1991.tb00581.x
发表时间：
1991-08
期刊：
Alcoholism, clinical and experimental research
影响因子：
--
作者：
M. Ronis;C. Lumpkin;Magnus Ingelman-Sundberg;T. M. Badger
通讯作者：
M. Ronis;C. Lumpkin;Magnus Ingelman-Sundberg;T. M. Badger
雄性大鼠慢性胃内乙醇输注期间乙醇的间歇性排泄：连续与循环乙醇和营养物输注。
DOI：
--
发表时间：
1993
期刊：
The Journal of pharmacology and experimental therapeutics
影响因子：
--
作者：
Badger,TM;Crouch,J;Irby,D;Hakkak,R;Shahare,M
通讯作者：
Shahare,M
DOI：
10.1006/bbrc.2000.3186
发表时间：
2000-08-11
影响因子：
3.1
作者：
Badger, TM;Hoog, JO;Ingelman-Sundberg, M
通讯作者：
Ingelman-Sundberg, M