Thirty-year follow-up of the NICHD Study of Early Child Care and Youth Development (SECCYD): the challenges and triumphs of conducting in-person research at a distance.

Thirty-year follow-up of the NICHD Study of Early Child Care and Youth Development (SECCYD): the challenges and triumphs of conducting in-person research at a distance.
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DOI:
10.1136/bmjopen-2022-066655
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发表时间:
2023-03-20
期刊:
影响因子:
2.9
通讯作者:
--
中科院分区:
医学3区
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--
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目前这项研究的目的是,国家儿童健康与人类发展研究所(NICHD)的早期和成人生活健康研究(SIRE),旨在通过对现已成年的参与者进行以健康为重点的后续行动,在1991年启动的纵向出生队列早期儿童保育和青年发展(SECCYD)这一里程碑式研究的基础上再接再厉。这一努力为探索生命历程研究提供了宝贵的资源,研究早期生命风险和复原力因素与成年后健康和疾病风险之间的联系。在本研究中可供招募的927名NICHD SECCYD参与者中,705人(76.1%)参与了这项研究。参与者年龄在26岁到31岁之间,生活在美国各地的不同地理位置。在描述性分析中,样本显示了健康状况指标的风险,特别是与肥胖、高血压和糖尿病有关的风险。尤其令人担忧的是,高血压(29.4%)和糖尿病(25.8%)的患病率超过了国家对同龄人群的估计。健康行为指标通常跟踪健康状况不佳的参数,显示出饮食不佳、活动不足和睡眠中断的模式。值得注意的是,样本相对较年轻的年龄(平均为28.6岁)和高教育程度(55.6%受过大学或以上教育)与其较差的健康状况并列在一起,这表明健康与通常具有健康保护作用的因素之间存在脱节。这与观察到的人群健康趋势是一致的,这表明美国年轻一代的心脏代谢健康状况正在恶化。目前的研究SINE为未来的分析奠定了基础,在这些分析中,作为最初NICHD SECCYD的一部分收集的独特的稳健测量将被用来精确定位特定的早期生命风险和复原力因素,以及解释青年时期健康和疾病风险指标变异性的相关因素和潜在机制。
The purpose of the current study, The National Institute of Child Health and Human Development (NICHD) Study of Health in Early and Adult Life (SHINE), was to build on the landmark Study of Early Child Care and Youth Development (SECCYD), a longitudinal birth cohort initiated in 1991, by conducting a health-focused follow-up of the now adult participants. This effort has produced an invaluable resource for the pursuit of life course research examining links between early life risk and resilience factors and adulthood health and disease risk. Of the 927 NICHD SECCYD participants available for recruitment in the current study, 705 (76.1%) participated in the study. Participants were between 26 and 31 years and living in diverse geographic locations throughout the USA. In descriptive analyses, the sample exhibited risk on health status indicators, especially related to obesity, hypertension and diabetes. Of particular concern, the prevalence of hypertension (29.4%) and diabetes (25.8%) exceeded national estimates in similar-age individuals. Health behaviour indicators generally tracked with the parameters of poor health status, showing a pattern of poor diet, low activity and disrupted sleep. The juxtaposition of the sample’s relatively young age (mean=28.6 years) and high educational status (55.6% college educated or greater) with its poor health status is noteworthy, suggesting a dissociation between health and factors that are typically health protective. This is consistent with observed population health trends, which show a worsening of cardiometabolic health status in younger generations of Americans. The current study, SHINE, lays the groundwork for future analyses in which the uniquely robust measures collected as a part of the original NICHD SECCYD will be leveraged to pinpoint specific early life risk and resilience factors as well as the correlates and potential mechanisms accounting for variability in health and disease risk indicators in young adulthood.
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