Childhood adversity and pubertal timing: understanding the origins of adulthood cardiovascular risk.
Childhood adversity and pubertal timing: understanding the origins of adulthood cardiovascular risk.
复制标题
DOI：
10.1016/j.biopsycho.2013.02.005
复制
发表时间：
2013-04
影响因子：
2.6
通讯作者：
Cedars, Marcelle I.
中科院分区：
文献类型：
--
作者：
Bleil, Maria E.;Adler, Nancy E.;Appelhans, Bradley M.;Gregorich, Steven E.;Sternfeld, Barbara;Cedars, Marcelle I.
确定更大的童年逆境是否与更年轻的初潮年龄有关；初潮年龄较小是否与心血管疾病风险增加有关；以及童年时期更大的逆境是否直接或间接（由初潮年龄介导）与心血管疾病风险增加有关。在 650 名绝经前女性（25-45 岁；M=34.9[5.6]）中，进行 SEM 来评估童年不幸、初潮年龄和 CVD 风险之间的关系。结果支持协变量调整模型（RMSEA=0.035；CFI=0.983），其中较大的童年逆境与较年轻的初潮年龄相关（β=−.13，p<.01），较年轻的初潮年龄与较高的 CVD 风险相关（β=−.18，p<.05）。童年不幸对心血管疾病风险的直接和间接影响并不显着。对同一模型的重新评估以及对成年身体成分的额外协变量调整表明，初潮年龄和 CVD 风险之间的关系减弱（β=−.03，p=.376）。横断面证据表明，童年时期与家庭相关的逆境经历会增加初潮提前的风险，而这反过来又可能通过青春期后的体型增加成年后心血管疾病的风险。
To determine whether greater childhood adversity relates to younger menarcheal age; whether younger menarcheal age relates to increased CVD risk; and whether greater childhood adversity relates to increased CVD risk, directly or indirectly (mediated by menarcheal age). Among 650 pre-menopausal women (ages 25-45; M=34.9[5.6]), SEM was performed to estimate relations between childhood adversity, menarcheal age, and CVD risk. Results supported a covariate-adjusted model (RMSEA=0.035; CFI=0.983) in which greater childhood adversity was related to younger menarcheal age (β=−.13, p<.01) and younger menarcheal age was related to greater CVD risk (β=−.18, p<.05). Direct and indirect effects of childhood adversity on CVD risk were non-significant. Re-evaluation of the same model with additional covariate-adjustment for adulthood body composition showed the relation between menarcheal age and CVD risk attenuated (β=−.03, p=.376). Cross-sectional evidence suggests family-related adversity experiences in childhood confer risk for earlier menarche which, in turn, relates to increased CVD risk in adulthood, possibly via post-pubertal body size.
登录
查看更多内容
影响因子：
5.4
作者：
Cooper, GS;Ephross, SA;Sandler, DP
通讯作者：
Sandler, DP
DOI：
10.1207/s15328007sem1001_2
发表时间：
2003-01-01
期刊：
STRUCTURAL EQUATION MODELING
影响因子：
--
作者：
Hershberger, SL
通讯作者：
Hershberger, SL
影响因子：
7.7
作者：
Jacobsen, B. K.;Oda, K.;Fraser, G. E.
通讯作者：
Fraser, G. E.
影响因子：
5.1
作者：
FISHER, M;ROSENFELD, WD;BURK, RD
通讯作者：
BURK, RD
影响因子：
5.3
作者：
Feng, Yan;Hong, Xiumei;Xu, Xin
通讯作者：
Xu, Xin