Amygdala-cingulate intrinsic connectivity is associated with degree of social inhibition.
Amygdala-cingulate intrinsic connectivity is associated with degree of social inhibition.
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DOI：
10.1016/j.biopsycho.2014.02.003
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发表时间：
2014-05
影响因子：
2.6
通讯作者：
VanDerKlok, Ross M.
中科院分区：
文献类型：
--
作者：
Blackford, Jennifer Urbano;Clauss, Jacqueline A.;Avery, Suzanne N.;Cowan, Ronald L.;Benningfield, Margaret M.;VanDerKlok, Ross M.
接近或回避陌生人的倾向是一种基本的人类行为，也是社交焦虑的一个核心维度。静息态功能磁共振成像被用于检测40名社交抑制程度从低到高的年轻人的社交抑制与内在连接之间的关联。较高水平的社交抑制与杏仁核 - 扣带回皮质连接性降低的特定模式有关。浅表层杏仁核与喙侧扣带回皮质之间以及中央内侧杏仁核与背侧前扣带回皮质之间的连接性降低。社交抑制还调节了几个已确立的内在网络的连接性；较高的社交抑制与默认模式网络和背侧注意网络的连接性降低以及显著网络和执行控制网络的连接性增强相关。这些发现提供了重要的初步证据，表明在没有社交刺激或应激源的情况下，社交抑制反映了大脑潜在内在连接的差异。
The tendency to approach or avoid novel people is a fundamental human behavior and is a core dimension of social anxiety. Resting state fMRI was used to test for an association between social inhibition and intrinsic connectivity in 40 young adults ranging from low to high in social inhibition. Higher levels of social inhibition were associated with specific patterns of reduced amygdala-cingulate cortex connectivity. Connectivity was reduced between the superficial amygdala and the rostral cingulate cortex and between the centromedial amygdala and the dorsal anterior cingulate cortex. Social inhibition also modulated connectivity in several well-established intrinsic networks; higher social inhibition correlated with reduced connectivity with default mode and dorsal attention networks and enhanced connectivity in salience and executive control networks. These findings provide important preliminary evidence that social inhibition reflects differences in the underlying intrinsic connectivity of the brain in the absence of social stimuli or stressors.
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DOI：
10.1097/chi.0b013e3181ae09df
发表时间：
2009-09
影响因子：
13.3
作者：
Chronis-Tuscano A;Degnan KA;Pine DS;Perez-Edgar K;Henderson HA;Diaz Y;Raggi VL;Fox NA
通讯作者：
Fox NA
影响因子：
4.2
作者：
Blackford, Jennifer Urbano;Avery, Suzanne N.;Zald, David H.
通讯作者：
Zald, David H.
影响因子：
--
作者：
Beesdo, Katja;Bittner, Antje;Wittchen, Hans-Ulrich
通讯作者：
Wittchen, Hans-Ulrich
影响因子：
25.8
作者：
Doehrmann, Oliver;Ghosh, Satrajit S.;Polli, Frida E.;Reynolds, Gretchen O.;Horn, Franziska;Keshavan, Anisha;Triantafyllou, Christina;Saygin, Zeynep M.;Whitfield-Gabrieli, Susan;Hofmann, Stefan G.;Pollack, Mark;Gabrieli, John D.
通讯作者：
Gabrieli, John D.
影响因子：
5.7
作者：
Diekhof, Esther Kristina;Geier, Katharina;Gruber, Oliver
通讯作者：
Gruber, Oliver