Cerebral White Matter Myelination and Relations to Age, Gender, and Cognition: A Selective Review.
Cerebral White Matter Myelination and Relations to Age, Gender, and Cognition: A Selective Review.
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DOI：
10.3389/fnhum.2021.662031
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发表时间：
2021
影响因子：
2.9
通讯作者：
Arsalidou M
中科院分区：
文献类型：
--
作者：
Buyanova IS;Arsalidou M
白色物质约占人脑的百分之五十。白色物质的成熟伴随着生物发育，并在儿童期和青春期经历最戏剧性的变化。尽管神经影像学技术取得了进展，但关于髓鞘形成的空间和时间模式以及白色物质的微结构特征在健康大脑中作为年龄、性别和认知能力的函数而变化的程度的争议仍然存在。在选择性综述中，我们描述了评估髓鞘形成的方法，并评估了9个主要纤维束中年龄和性别的影响，强调了它们在高阶认知功能中的作用。我们的研究结果表明，髓鞘形成指数随年龄，纤维束和半球而变化。还查明了性别的影响，尽管有些人将差异归因于方法因素或社会和学习机会。研究结果指出了进一步的研究方向，这将提高我们对整个发展过程中复杂的髓鞘形成-行为关系的理解，这可能对教育和临床实践产生影响。
White matter makes up about fifty percent of the human brain. Maturation of white matter accompanies biological development and undergoes the most dramatic changes during childhood and adolescence. Despite the advances in neuroimaging techniques, controversy concerning spatial, and temporal patterns of myelination, as well as the degree to which the microstructural characteristics of white matter can vary in a healthy brain as a function of age, gender and cognitive abilities still exists. In a selective review we describe methods of assessing myelination and evaluate effects of age and gender in nine major fiber tracts, highlighting their role in higher-order cognitive functions. Our findings suggests that myelination indices vary by age, fiber tract, and hemisphere. Effects of gender were also identified, although some attribute differences to methodological factors or social and learning opportunities. Findings point to further directions of research that will improve our understanding of the complex myelination-behavior relation across development that may have implications for educational and clinical practice.
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影响因子：
5.7
作者：
Arshad M;Stanley JA;Raz N
通讯作者：
Raz N
影响因子：
--
作者：
Bartzokis, G;Beckson, M;Mintz, J
通讯作者：
Mintz, J
影响因子：
3.1
作者：
Andre, Quinn R.;Geeraert, Bryce L.;Lebel, Catherine
通讯作者：
Lebel, Catherine
影响因子：
3.7
作者：
Asato, M. R.;Terwilliger, R.;Luna, B.
通讯作者：
Luna, B.
影响因子：
5.3
作者：
Aron, Adam R.;Behrens, Tim E.;Poldrack, Russell A.
通讯作者：
Poldrack, Russell A.