Smooth pursuit eye movements in 1,087 men: effects of schizotypy, anxiety, and depression
Smooth pursuit eye movements in 1,087 men: effects of schizotypy, anxiety, and depression
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1,087 名男性的平滑追踪眼球运动：精神分裂、焦虑和抑郁的影响
DOI：
--
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发表时间：
2007
影响因子：
2
通讯作者：
C. Stefanis
中科院分区：
文献类型：
--
作者：
N. Smyrnis;I. Evdokimidis;Asimakis Mantas;E. Kattoulas;N. Stefanis;T. Constantinidis;D. Avramopoulos;C. Stefanis
患有分裂型人格障碍或在分裂型问卷中得分较高的个体患精神分裂症的风险较高，他们也有一些相同的表型特征，如眼动追踪功能障碍（ETD）。问题是这些个体是否在普通人群中形成了一个明显的高风险群体，或者精神分裂型和ETD是否在普通人群中共同变化，而对高风险群体没有明显的截止点。为了对精神病发展的易感性因素进行前瞻性研究，我们使用眼动、认知和心理测量工具对年龄在18-25岁之间的应征军人进行了筛选。使用知觉偏差量表（PAS）和分裂型人格问卷（SPQ）测量的分裂型，使用症状检查表90-R测量的焦虑和抑郁对总样本的追求表现没有影响。然后确定在精神分裂问卷中得分很高的一小群人。这些群体并不相互排斥。高PAS组的均方根误差得分（追求质量的定量衡量指标）高于总体样本，高无序因子SPQ组的追求增益低于总体样本，扫视频率高于总体样本。只有预先确定的高分裂型群体在追求表现上存在显著差异，这支持了一种假设，即高分裂型个体可能存在一个或多个与一般人群不同的高风险群体，这些群体容易发生ETD，正如在精神分裂症中观察到的那样。
Individuals with schizotypal personality disorder or high scores in questionnaires measuring schizotypy are at high risk for the development of schizophrenia and they also share some of the same phenotypic characteristics such as eye-tracking dysfunction (ETD). The question arises whether these individuals form a distinct high-risk group in the general population or whether schizotypy and ETD co-vary in the general population with no distinct cutoff point for a high-risk group. A large sample of military conscripts aged 18–25 were screened using oculomotor, cognitive and psychometric tools for the purposes of a prospective study on predisposing factors for the development of psychosis. Schizotypy measured using the perceptual aberration scale (PAS) and the schizotypal personality questionnaire (SPQ), anxiety and depression, measured using the Symptom Checklist 90-R, had no effect on pursuit performance in the total sample. Small groups of individuals with very high scores in schizotypy questionnaires were then identified. These groups were not mutually exclusive. The high PAS group had higher root-mean-square error scores (a quantitative measure for pursuit quality) than the total sample, and the high disorganized factor of SPQ group had lower gain and higher saccade frequencies in pursuit than the total sample. The presence of significant differences in pursuit performance only for predefined high schizotypy groups favors the hypothesis that individuals with high schizotypy might present one or more high-risk groups, distinct from the general population, that are prone to ETD as that observed in schizophrenia.
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影响因子：
4.6
作者：
CHAPMAN, LJ;CHAPMAN, JP;ZINSER, MC
通讯作者：
ZINSER, MC
谱系人格障碍中的眼球运动：社区受试者和精神分裂症患者亲属的比较。
DOI：
10.1176/ajp.153.3.362
发表时间：
1996
期刊：
The American journal of psychiatry.
影响因子：
--
作者：
Thaker,GK;Cassady,S;Adami,H;Moran,M;Ross,DE
通讯作者：
Ross,DE
影响因子：
6.6
作者：
Reynolds, CA;Raine, A;Mednick, SA
通讯作者：
Mednick, SA
影响因子：
--
作者：
CLONINGER, CR;SVRAKIC, DM;PRZYBECK, TR
通讯作者：
PRZYBECK, TR
青春期前、青春期和成年期动眼神经功能的发展。
DOI：
--
发表时间：
1998
期刊：
Psychophysiology.
影响因子：
--
作者：
Katsanis,J;Iacono,WG;Harris,M
通讯作者：
Harris,M