Distribution of quinolones, sulfonamides, tetracyclines in aquatic environment and antibiotic resistance in indochina.

Distribution of quinolones, sulfonamides, tetracyclines in aquatic environment and antibiotic resistance in indochina.
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DOI:
10.3389/fmicb.2012.00067
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发表时间:
2012
影响因子:
5.2
通讯作者:
Hoa PT
Hoa PT
中科院分区:
生物学2区
文献类型:
--
作者:
Suzuki S;Hoa PT

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东南亚已成为工业快速发展和经济增长的中心。然而,这种增长远远超过了对公共基础设施的投资,导致许多污染物的无管制排放,包括与废水有关的污染物,如抗生素。抗生素是主要关注的问题,因为它们很容易从许多来源释放到环境中,并可能随后诱导抗生素耐药细菌的发展。最近的研究表明,对于某些类别的药物,这种来源-环境抗生素耐药性关系更为复杂。本文综述了目前对印度支那水生环境中喹诺酮类、磺胺类和四环素类药物的存在及其耐药细菌的流行情况的了解。本文讨论了几个值得注意的发现:(1)喹诺酮污染与喹诺酮类药物耐药性的发生不相关;(2)磺胺抗性基因发生的地理差异;(3)微生物多样性可能与土霉素耐药率有关。
Southeast Asia has become the center of rapid industrial development and economic growth. However, this growth has far outpaced investment in public infrastructure, leading to the unregulated release of many pollutants, including wastewater-related contaminants such as antibiotics. Antibiotics are of major concern because they can easily be released into the environment from numerous sources, and can subsequently induce development of antibiotic-resistant bacteria. Recent studies have shown that for some categories of drugs this source-to-environment antibiotic resistance relationship is more complex. This review summarizes current understanding regarding the presence of quinolones, sulfonamides, and tetracyclines in aquatic environments of Indochina and the prevalence of bacteria resistant to them. Several noteworthy findings are discussed: (1) quinolone contamination and the occurrence of quinolone resistance are not correlated; (2) occurrence of the sul sulfonamide resistance gene varies geographically; and (3) microbial diversity might be related to the rate of oxytetracycline resistance.
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