Informatics and quantitative analysis in biological imaging.
Informatics and quantitative analysis in biological imaging.
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DOI:
10.1126/science.1082602
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发表时间:
2003-04-04
期刊:
影响因子:
--
通讯作者:
Sorger PK
中科院分区:
文献类型:
--
作者:
Swedlow JR;Goldberg I;Brauner E;Sorger PK
Biological imaging is now a quantitative technique for probing cellular structure and dynamics, and increasingly for cell-based screens. However, the bioinformatics tools required for hypothesis-driven analysis of digital images are still immature. We are developing the Open Microscopy Environment (OME) as an informatics solution for the storage and analysis of optical microscope image data. OME aims to automate image analysis, modeling and mining of large sets of images and specifies a flexible data model, a relational database, and an XML-encoded file standard usable by potentially any software tool. With this design, OME provides a first step toward biological image informatics.
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