Dissociated resting-state functional networks between the dream recall frequency and REM sleep percentage
Dissociated resting-state functional networks between the dream recall frequency and REM sleep percentage
复制标题
梦回忆频率和快速眼动睡眠百分比之间分离的静息态功能网络。
DOI：
10.1016/j.neuroimage.2018.03.015
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发表时间：
2018-07
期刊：
影响因子：
5.7
通讯作者：
Gao J. H.
中科院分区：
文献类型：
--
作者：
Zou Q;Zhou S;Xu J;Su Z;Li Y;Ma Y;Sun H;Wu C. W;Gao J. H.
快速眼动（REM）睡眠经常与做梦有关。然而，从行为学、药理学和脑成像研究中获得的越来越多的证据表明，REM睡眠并不代表梦的报告，可能源于大脑功能中的不同神经基质。本研究的目的是通过评估静息状态下的功能连接，探讨与梦回忆和REM睡眠个体间差异相关的功能系统。我们收集了43名健康成年志愿者（23名男性）睡眠前后的静息状态功能磁共振成像（fMRI）数据，用于功能连接评估。为了评估梦的回忆频率，所有志愿者保持2周的睡眠日记。此外，还进行了整夜多导睡眠描记术以测量REM睡眠百分比。采用一般线性模型分析法对12个感兴趣的功能连接网络与梦回忆频率和REM睡眠百分比进行了体素相关分析。梦回忆频率和REM睡眠百分比与多个脑功能网络呈负相关。然而，梦回忆频率主要与外侧视觉网络和丘脑内的功能连接有关，而REM睡眠百分比主要与额顶网络和小脑内的连接有关。此外，梦回忆频率在夜间与侧视觉网络连接性之间显示出更强的耦合，而REM睡眠百分比与小脑之间的耦合在早晨更高。这表明一天中的时间效应显著。我们的研究结果提供了神经影像学证据，证明与梦回忆频率相关的功能系统不同于与REM睡眠百分比相关的功能系统。
Rapid eye movement (REM) sleep has been frequently associated with dreaming. However, mounting evidence obtained from behavioral, pharmacological, and brain imaging studies suggests that REM sleep is not indicative of the dream report and may originate from diverse neural substrates in brain functionality. The aim of the current study was to investigate the functional systems associated with inter-individual differences in dream recall and REM sleep through assessments of the resting-state functional connectivity. We collected resting-state functional magnetic resonance imaging (fMRI) data for functional connectivity evaluations from 43 healthy adult volunteers (23 men) before and after sleep. For assessment of the dream recall frequency, a 2-week sleep diary was maintained by all volunteers. In addition, whole-night polysomnography was performed for measuring the REM sleep percentage. Voxel-wise correlation analyses of 12 functional connectivity networks of interest with the dream recall frequency and REM sleep percentage were conducted using general linear model analysis. Both the dream recall frequency and REM sleep percentage showed negative associations with multiple brain functional networks. However, the dream recall frequency was mainly related to functional connectivity within the lateral visual network and thalamus, whereas the REM sleep percentage was mainly associated with connectivity within the frontoparietal networks and cerebellum. In addition, the dream recall frequency showed stronger coupling with the lateral visual network connectivity at night, whereas the coupling between the REM sleep percentage and cerebellum was higher in the morning. This indicated a significant time of day effect. Our results provide neuroimaging evidence that the functional system associated with the dream recall frequency is different from that associated with the REM sleep percentage.
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影响因子：
5.3
作者：
Byrne, Jamie E. M.;Hughes, Matthew E.;Murray, Greg
通讯作者：
Murray, Greg
DOI：
--
发表时间：
1991
期刊：
--
影响因子：
--
作者：
D. Goodenough
通讯作者：
D. Goodenough
影响因子：
5.7
作者：
Satterthwaite, Theodore D.;Wolf, Daniel H.;Loughead, James;Ruparel, Kosha;Elliott, Mark A.;Hakonarson, Hakon;Gur, Ruben C.;Gur, Raquel E.
通讯作者：
Gur, Raquel E.
影响因子：
4.8
作者：
Peraza, Luis R.;Nesbitt, David;Taylor, John-Paul
通讯作者：
Taylor, John-Paul
影响因子：
5.6
作者：
Khalsa, Sakh;Mayhew, Stephen D.;Bagshaw, Andrew P.
通讯作者：
Bagshaw, Andrew P.