The cruciform model of striate generation of the early VEP, re-illustrated, not revoked: a reply to Ales et al. (2013).

The cruciform model of striate generation of the early VEP, re-illustrated, not revoked: a reply to Ales et al. (2013).
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DOI:
10.1016/j.neuroimage.2013.05.112
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发表时间:
2013-11-15
期刊:
影响因子:
5.7
通讯作者:
Lalor EC
Lalor EC
中科院分区:
医学1区
文献类型:
--
作者:
Kelly SP;Vanegas MI;Schroeder CE;Lalor EC

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在这里,我们总结了在与Ales和同事就早期视觉诱发电位(VEP)的皮层发生器的对话中提出的观点,并提供了对响应我们最初评论而运行的其他模拟结果的观察。对于放置在人类VEP已经很好表征的上下视野位置的小刺激,模拟头皮V1、V2和V3视觉区域的投影在极性上颠倒。然而,经验测量的最早的VEP组件“C1”在极性和地形方面与模拟的V1发生器匹配,但与模拟的V2和V3发生器不匹配。因此,我们得出结论:1)与标题一致,极性反转本身并不是推断初级视觉皮层神经电源的充分标准;但2)与中提出的其他主张不一致,模拟地形提供了支持(而不是反对)C1成分产生于V1的原则的额外证据。
Here we summarize the points raised in our dialogue with Ales and colleagues on the cortical generators of the early visual evoked potential (VEP), and offer observations on the results of additional simulations that were run in response to our original comment. For small stimuli placed at locations in the upper and lower visual field for which the human VEP has been well characterized, simulated scalp projections of each of the visual areas V1, V2 and V3 invert in polarity. However, the empirically measured, earliest VEP component, “C1,” matches the simulated V1 generators in terms of polarity and topography, but not the simulated V2 and V3 generators. We thus conclude that, 1) consistent with the title of, polarity inversion on its own is not a sufficient criterion for inferring neuroelectric sources in primary visual cortex; but 2) inconsistent with additional claims made in, the simulated topographies provide additional evidence for – not against – the tenet that the C1 component is generated in V1.
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