Subcellular Organization: A Critical Feature of Bacterial Cell Replication.

Subcellular Organization: A Critical Feature of Bacterial Cell Replication.
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DOI:
10.1016/j.cell.2018.01.014
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发表时间:
2018-03-08
期刊:
影响因子:
64.5
通讯作者:
Jacobs-Wagner C
Jacobs-Wagner C
中科院分区:
生物学1区
文献类型:
--
作者:
Surovtsev IV;Jacobs-Wagner C

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空间组织是所有生命系统的标志。即使是细菌,细胞生命的最小形式,也显示出确定的形状和复杂的内部组织,展示了高度结构化的基因组,细胞骨架丝,局部支架结构,动态空间模式,主动运输,偶尔还有细胞内细胞器。空间秩序是忠实和有效的细胞复制所必需的,并为独特的生物学特性的发展提供了强有力的手段。在这里,我们讨论了细菌细胞的组织特征,并强调了细菌如何进化出不同的空间机制,以克服细胞作为自我复制实体所面临的挑战。
Spatial organization is a hallmark of all living systems. Even bacteria, the smallest forms of cellular life, display defined shapes and complex internal organization showcasing a highly structured genome, cytoskeletal filaments, localized scaffolding structures, dynamic spatial patterns, active transport, and occasionally intracellular organelles. Spatial order is required for faithful and efficient cellular replication, and offers a powerful means for the development of unique biological properties. Here, we discuss organizational features of bacterial cells and highlight how bacteria have evolved diverse spatial mechanisms to overcome challenges cells face as self-replicating entities.
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