Multistep liquid-phase lithography for fast prototyping of microfluidic free-flow-electrophoresis chips
Multistep liquid-phase lithography for fast prototyping of microfluidic free-flow-electrophoresis chips
复制标题
用于微流控自由流动电泳芯片快速原型制作的多步液相光刻
DOI:
10.1007/s00216-011-5351-2
复制
发表时间:
2011
影响因子:
4.3
通讯作者:
D. Belder
中科院分区:
文献类型:
--
作者:
S. Jezierski;L. Gitlin;S. Nagl;D. Belder
We present a fast and versatile method to produce functional micro free-flow electrophoresis chips. Microfluidic structures were generated between two glass slides applying multistep liquid-phase lithography, omitting troublesome bonding steps or cost-intensive master structures. Utilizing a novel spacer-less approach with the photodefinable polymer polyethyleneglycol dimethacrylate (PEG-DA), microfluidic devices with hydrophilic channels of only 25 μm in height were generated. The microfluidic chips feature ion-permeable segregation walls between the electrode channels and the separation bed and hydrophilic surfaces. The performance of the chip is demonstrated by free-flow electrophoretic separation of fluorescent xanthene dyes and fluorescently labeled amino acids.
登录
查看更多内容
DOI:
--
发表时间:
2011
期刊:
MOEMS-MEMS
影响因子:
--
作者:
Stefan Köhler;H. Becker;V. Beushausen;W. Hüttner;H. Wackerbarth;E. Beckert;S. Howitz;D. Belder
通讯作者:
D. Belder
影响因子:
7.4
作者:
Zhang, CX;Manz, A
通讯作者:
Manz, A
影响因子:
2.9
作者:
D. Belder;A. Deege;M. Maass;M. Ludwig
通讯作者:
M. Ludwig
影响因子:
6.1
作者:
Xu, Y;Zhang, CX;Manz, A
通讯作者:
Manz, A
影响因子:
6.1
作者:
Kohlheyer, D;Besselink, GAJ;Schasfoort, RBM
通讯作者:
Schasfoort, RBM