Chronic treatment with trimetazidine reduces the upregulation of atrial natriuretic peptide in heart failure.
Chronic treatment with trimetazidine reduces the upregulation of atrial natriuretic peptide in heart failure.
复制标题
曲美他嗪的长期治疗可减少心力衰竭时心房钠尿肽的上调。
DOI:
10.1111/j.1472-8206.2006.00424.x
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发表时间:
2006
影响因子:
2.9
通讯作者:
Stanley,WilliamC
中科院分区:
文献类型:
--
作者:
Morgan,EricE;Young,MartinE;McElfresh,TracyA;Kung,TheodoreA;Hoit,BrianD;Chandler,MargaretP;Stanley,WilliamC
Trimetazidine (TMZ) is effective for the treatment of ischemic cardiomyopathy; however, little is known about the effect of TMZ in established injury‐induced heart failure. When rats with established infarct‐induced heart failure were treated for 12 weeks with TMZ there was no effect on left ventricular function or dilation, or on mRNA expression of fatty acid oxidation enzymes. On the other hand, TMZ significantly reduced atrial natriuretic peptide mRNA levels compared with untreated rats.
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影响因子:
16.2
作者:
BARNARD, RJ;MASSEY, MR;PRITIKIN, N
通讯作者:
PRITIKIN, N
影响因子:
5.3
作者:
M. Antar;J. Little;C. Lucas;G. Buckley;A. Csima
通讯作者:
A. Csima
影响因子:
7.7
作者:
O. Kolterman;M. Greenfield;G. Reaven;M. Saekow;J. Olefsky
通讯作者:
J. Olefsky
DOI:
10.1152/ajplegacy.1964.206.1.105
发表时间:
1964
期刊:
The American journal of physiology
影响因子:
--
作者:
A. Cohen;A. Teitelbaum
通讯作者:
A. Teitelbaum
影响因子:
--
作者:
G. Grimditch;R. Barnard;E. Sternlicht;R. Whitson;S. Kaplan
通讯作者:
S. Kaplan