Simulation of electric potentials and ion motion in planar electrode structures for lossless ion manipulations (SLIM).

Simulation of electric potentials and ion motion in planar electrode structures for lossless ion manipulations (SLIM).
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DOI:
10.1007/s13361-014-0976-y
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发表时间:
2014-11
影响因子:
3.2
通讯作者:
Smith, Richard D.
Smith, Richard D.
中科院分区:
化学3区
文献类型:
--
作者:
Garimella, Sandilya V. B.;Ibrahim, Yehia M.;Webb, Ian K.;Tolmachev, Aleksey V.;Zhang, Xinyu;Prost, Spencer A.;Anderson, Gordon A.;Smith, Richard D.

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我们报道了一种用于无损离子操纵(SLIM)的新型平面电极结构的概念研究和计算评估。设计了平面电极SLIM器件,允许使用RF和DC场组合进行灵活的离子约束,传输和存储。在存在气体的情况下,可以产生有效电位,为限制和操纵离子提供接近理想的区域。使用SIMION 8.1进行离子轨迹模拟,证明了这些设备在宽m/z范围和低压(例如几torr)的电场范围内无损离子运动的能力。更复杂的离子操作,例如将离子旋转90°并动态切换选定的离子种类到正交通道中,也被证明是可行的。对SLIM器件在~4 torr压力下进行离子迁移率分离(IMS)的性能进行了计算评估,并与初始实验结果进行了比较,两者也显示出与传统漂移管设计的实验和理论IMS性能密切一致。
We report a conceptual study and computational evaluation of novel planar electrode Structures for Lossless Ion Manipulations (SLIM). Planar electrode SLIM devices were designed that allow for flexible ion confinement, transport and storage using a combination of RF and DC fields. Effective potentials can be generated that provide near ideal regions for confining and manipulating ions in the presence of a gas. Ion trajectory simulations using SIMION 8.1 demonstrated the capability for lossless ion motion in these devices over a wide m/z range and a range of electric fields at low pressures (e.g. a few torr). More complex ion manipulations, e.g. turning ions by 90° and dynamically switching selected ion species into orthogonal channels, are also shown feasible. The performance of SLIM devices at ~4 torr pressure for performing ion mobility based separations (IMS) is computationally evaluated and compared to initial experimental results, and both of which are also shown to agree closely with experimental and theoretical IMS performance for a conventional drift tube design.
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