"Something Good Has to Come Out of the Horror": A Qualitative Examination of Cancer Survivors' Attitudes Towards Participation in Research During the First Year of the COVID-19 Pandemic.
"Something Good Has to Come Out of the Horror": A Qualitative Examination of Cancer Survivors' Attitudes Towards Participation in Research During the First Year of the COVID-19 Pandemic.
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DOI：
10.3389/fpubh.2021.741188
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发表时间：
2021
影响因子：
5.2
通讯作者：
Van Hemelrijck M
中科院分区：
文献类型：
--
作者：
Fox L;Wylie H;Haire A;Green S;Kibaru J;Van Hemelrijck M
简介：COVID-19大流行的第一年对癌症患者来说具有很大的破坏性。此外，癌症试验的累积在2020年大幅下降。本研究以先前试点调查的结果为基础，采用定性方法深入了解在COVID-19大流行的第一年背景下，癌症患者对参与研究的态度。材料与方法：我们采访了来自英国的13名参与者，他们是有目的地抽样的，包括广泛的癌症类型样本，以及以前参加过和没有参加过研究的个人的混合体。参与者接受了半结构化采访（采访时间中位数：47分钟），并被问及有关他们对COVID-19的态度和经历以及对研究参与的态度的开放式问题。除此之外，我们还使用提示来询问参与者关于我们之前关于这一主题的定量工作所强调的问题，例如对年龄较大或不得不旅行参加的担忧。访谈记录使用框架分析方法进行了分析。结果如下：我们的研究结果表明，在传染病大流行期间，癌症患者参与研究的决策可能是基本成本效益分析的一个功能，该分析考虑了参与研究的好处，无论是个人还是更广泛的社会。然后，患者可能会权衡受益与感染风险，这可能受到以下因素的影响：对相关临床医生/研究人员的信任;对研究地点的熟悉程度;提供有关传染病安全方案的详细信息;特别是往返研究地点的安全交通工具的可用性。讨论内容：一些癌症患者说，他们不太可能在传染病大流行期间参加研究，因为这会增加他们的风险。通过提供某些可在研究方案设计阶段考虑的实际解决方案，如安全旅行、信息以及使用患者熟悉的工作人员和研究中心，可以改善患者认为参与研究对自己造成的风险。
Introduction: The first year of the COVID-19 pandemic has been highly disruptive for people with cancer. Furthermore, it has been shown that accrual to cancer trials dropped substantially in 2020. Building on findings from a previous pilot survey, the present study used qualitative methods to gain insights into attitudes towards participation in research studies amongst people who have experienced cancer, in the context of the first year of the COVID-19 pandemic. Materials and Methods: We interviewed 13 participants from the UK, who were purposively sampled, including a broad sample of cancer types, and a mixture of individuals who have and have not taken part in research previously. Participants underwent semi-structured interviews (median interview duration: 47 min) and were asked open-ended questions about their attitude towards and experiences with COVID-19, and their attitude towards research participation. In addition to this, prompts were used to ask participants about concerns that were highlighted by our previous quantitative work on this topic, such as concerns about being older or having to travel to participate. Interview transcripts were analysed using a framework analysis approach. Results: Our findings suggest that cancer patient decision-making about research participation during an infectious disease pandemic may be a function of a basic cost-benefit analysis, which considers the benefit of taking part, either personally to themselves or to wider society. The benefit may then be weighed by the patient against the risk of being infected, which may be influenced by trust in the relevant clinicians/researchers; familiarity with the study location; provision of detailed information on safety protocols for infectious disease; and, in particular, the availability of safe transport to and from the study location. Discussion: Some cancer patients say that they would be less likely to participate in a research study in the middle of an infectious disease pandemic due to an increased risk to themselves. Patients' perceived risk to themselves from participating may be ameliorated via the provision of certain practical solutions that can be considered at the study protocol design stage, such as safe travel, information, and the use of staff and study sites familiar to the patient.
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影响因子：
6.2
作者：
Dang, Julie H. T.;Chen, Moon S., Jr.
通讯作者：
Chen, Moon S., Jr.
DOI：
10.1177/1073274821989315
发表时间：
2021-01
期刊：
Cancer control : journal of the Moffitt Cancer Center
影响因子：
--
作者：
Fox L;Wylie H;Cahill F;Haire A;Green S;Kibaru J;Hartley C;Sullivan R;Van Hemelrijck M
通讯作者：
Van Hemelrijck M
DOI：
10.1158/1078-0432.ccr-20-3421
发表时间：
2021-01-01
期刊：
Clinical cancer research : an official journal of the American Association for Cancer Research
影响因子：
--
作者：
Newman LA;Winn RA;Carethers JM
通讯作者：
Carethers JM
影响因子：
6.2
作者：
Westrick, Ashly C.;Bailey, Zinzi D.;Balise, Raymond R.
通讯作者：
Balise, Raymond R.
影响因子：
1.4
作者：
Scharff, Darcell P.;Mathews, Katherine J.;Edwards, Dorothy
通讯作者：
Edwards, Dorothy