Magnesium: Biochemistry, Nutrition, Detection, and Social Impact of Diseases Linked to Its Deficiency.
Magnesium: Biochemistry, Nutrition, Detection, and Social Impact of Diseases Linked to Its Deficiency.
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DOI：
10.3390/nu13041136
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发表时间：
2021-03-30
期刊：
影响因子：
5.9
通讯作者：
Prata C
中科院分区：
文献类型：
--
作者：
Fiorentini D;Cappadone C;Farruggia G;Prata C
镁在许多生理功能中起着重要作用。镁的习惯性低摄入量和这种微量营养素的普遍缺乏会引起生化途径的变化，从而增加患病风险，特别是慢性退行性疾病的风险。因此，评价镁的状态是非常重要的，但它的评价是困难的。测定血清镁浓度是评估镁状态最常用和最容易获得的方法，即使血清水平与全身镁水平或特定组织中的浓度没有可靠的相关性。因此，本文从多个角度综述了镁的最新研究进展。从生物化学的角度出发，其目的是强调摄取不足（通常是由于现代西方饮食中镁含量低）所造成的风险，提出达到推荐膳食参考值的策略，并强调检测身体各部位镁的生理或病理水平的重要性，以抵消与缺镁有关的疾病的社会影响。
Magnesium plays an important role in many physiological functions. Habitually low intakes of magnesium and in general the deficiency of this micronutrient induce changes in biochemical pathways that can increase the risk of illness and, in particular, chronic degenerative diseases. The assessment of magnesium status is consequently of great importance, however, its evaluation is difficult. The measurement of serum magnesium concentration is the most commonly used and readily available method for assessing magnesium status, even if serum levels have no reliable correlation with total body magnesium levels or concentrations in specific tissues. Therefore, this review offers an overview of recent insights into magnesium from multiple perspectives. Starting from a biochemical point of view, it aims at highlighting the risk due to insufficient uptake (frequently due to the low content of magnesium in the modern western diet), at suggesting strategies to reach the recommended dietary reference values, and at focusing on the importance of detecting physiological or pathological levels of magnesium in various body districts, in order to counteract the social impact of diseases linked to magnesium deficiency.
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影响因子：
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