Extensive Independent Amplification of Platy-1 Retroposons in Tamarins, Genus Saguinus.
Extensive Independent Amplification of Platy-1 Retroposons in Tamarins, Genus Saguinus.
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DOI：
10.3390/genes14071436
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发表时间：
2023-07-13
期刊：
影响因子：
3.5
通讯作者：
Batzer, Mark A.
中科院分区：
文献类型：
--
作者：
Storer, Jessica M.;Walker, Jerilyn A.;Beckstrom, Thomas O.;Batzer, Mark A.
Platy-1反转座子是阔鼻灵长类动物特有的短散布元件（西内斯）。这些100 bp的移动的元件插入（MEI）于2016年在普通绒猴（Callithrix jacchus）基因组中发现，似乎是阔鼻猴进化的新驱动因素，在62个不同的亚科中有超过2200个全长成员，并且有强有力的证据表明C.雅克斯随后的特征的Platy-1元素在Aotus，Saimiri和Cebus属，表明在绒猴（家庭Callithrichidae）检测到的广泛动员可能是一个异常。另外两个Callithrichidae基因组现在可用，Saguinus imperator（tamarin; SagImp_v1）的支架水平基因组组装和Saguinus midas（Midas tamarin; ASM2_v1）的染色体水平组装。在这里，我们报告说，每个绢毛猴基因组包含超过11,000全长Platy-1插入，约1150是共享的两个Saguinus绢毛猴，7511是唯一的S。imperator和另一个8187是S.迈达斯大约有325个是由三种Callithrichids共享的。我们鉴定了6个新的Platy-1亚家族，它们来自Platy-1-8，其中最年轻的新亚家族Platy-1-8c_Saguinus是Saguinus扩增爆发的主要来源。这是迄今为止报道的最大的Platy-1 MEI扩增，也是两个密切相关物种之间最广泛的独立SINE扩增。
Platy-1 retroposons are short interspersed elements (SINEs) unique to platyrrhine primates. Discovered in the common marmoset (Callithrix jacchus) genome in 2016, these 100 bp mobile element insertions (MEIs) appeared to be novel drivers of platyrrhine evolution, with over 2200 full-length members across 62 different subfamilies, and strong evidence of ongoing proliferation in C. jacchus. Subsequent characterization of Platy-1 elements in Aotus, Saimiri and Cebus genera, suggested that the widespread mobilization detected in marmoset (family Callithrichidae) was perhaps an anomaly. Two additional Callithrichidae genomes are now available, a scaffold level genome assembly for Saguinus imperator (tamarin; SagImp_v1) and a chromosome-level assembly for Saguinus midas (Midas tamarin; ASM2_v1). Here, we report that each tamarin genome contains over 11,000 full-length Platy-1 insertions, about 1150 are shared by both Saguinus tamarins, 7511 are unique to S. imperator, and another 8187 are unique to S. midas. Roughly 325 are shared among the three callithrichids. We identified six new Platy-1 subfamilies derived from Platy-1-8, with the youngest new subfamily, Platy-1-8c_Saguinus, being the primary source of the Saguinus amplification burst. This constitutes the largest expansion of Platy-1 MEIs reported to date and the most extensive independent SINE amplification between two closely related species.
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影响因子：
14.5
作者：
Konkel MK;Batzer MA
通讯作者：
Batzer MA
影响因子：
3.5
作者：
Storer, Jessica M. M.;Walker, Jerilyn A. A.;Rewerts, Lydia C. C.;Brown, Morgan A. A.;Beckstrom, Thomas O. O.;Herke, Scott W. W.;Roos, Christian;Batzer, Mark A. A.
通讯作者：
Batzer, Mark A. A.
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通讯作者：
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影响因子：
3.5
作者：
Storer, Jessica M.;Walker, Jerilyn A.;Rockwell, Catherine E.;Mores, Grayce;Beckstrom, Thomas O.;Orkin, Joseph D.;Melin, Amanda D.;Phillips, Kimberley A.;Roos, Christian;Batzer, Mark A.
通讯作者：
Batzer, Mark A.
影响因子：
4.1
作者：
Garbino, Guilherme S. T.;Martins-Junior, Antonio M. G.
通讯作者：
Martins-Junior, Antonio M. G.