Decomposing decision components in the stop-signal task: a model-based approach to individual differences in inhibitory control.
Decomposing decision components in the stop-signal task: a model-based approach to individual differences in inhibitory control.
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DOI：
10.1162/jocn_a_00567
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发表时间：
2014-08
影响因子：
3.2
通讯作者：
Poldrack RA
中科院分区：
文献类型：
--
作者：
White CN;Congdon E;Mumford JA;Karlsgodt KH;Sabb FW;Freimer NB;London ED;Cannon TD;Bilder RM;Poldrack RA
停止信号任务（SST）要求参与者必须抑制优势反应，该任务已被用来识别因抑制控制的个体差异而变化的神经系统。为了探索这些差异如何与决策的其他方面相关，我们将简单决策的漂移扩散模型与围棋试验的 SST 数据进行拟合，以提取 123 名参与者中每人的谨慎程度、运动执行时间和刺激处理速度的测量值。这些值用于探测功能磁共振成像数据，以探索神经激活的个体差异。在 Go 和 Stop 试验中，对 Go 刺激的更快处理与右额极的更大激活相关。在停止试验中，刺激处理速度也与抑制控制相关的区域相关，包括右额下回、额内侧回和基底神经节。运动执行时间的个体差异与右顶叶皮层的激活相关。这些发现表明神经水平上刺激处理和抑制处理的速度之间存在牢固的关系。这种基于模型的方法为抑制控制所涉及的决策成分之间的相互关系提供了新颖的见解，并提出了关于与精神病理学相关的表现和抑制缺陷的策略调整的有趣问题。
The Stop-signal task (SST), in which participants must inhibit prepotent responses, has been used to identify neural systems that vary with individual differences in inhibitory control. To explore how these differences relate to other aspects of decision-making, a drift diffusion model of simple decisions was fitted to SST data from Go trials to extract measures of caution, motor execution time, and stimulus processing speed for each of 123 participants. These values were used to probe fMRI data to explore individual differences in neural activation. Faster processing of the Go stimulus correlated with greater activation in the right frontal pole for both Go and Stop trials. On Stop trials stimulus processing speed also correlated with regions implicated in inhibitory control, including the right inferior frontal gyrus, medial frontal gyrus, and basal ganglia. Individual differences in motor execution time correlated with activation of the right parietal cortex. These findings suggest a robust relationship between the speed of stimulus processing and inhibitory processing at the neural level. This model-based approach provides novel insight into the interrelationships among decision components involved in inhibitory control, and raises interesting questions about strategic adjustments in performance and inhibitory deficits associated with psychopathology.
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影响因子：
5.7
作者：
Congdon, Eliza;Mumford, Jeanette A.;Cohen, Jessica R.;Galvan, Adriana;Aron, Adam R.;Xue, Gui;Miller, Eric;Poldrack, Russell A.
通讯作者：
Poldrack, Russell A.
影响因子：
5.7
作者：
Boehler, C. N.;Appelbaum, L. G.;Krebs, R. M.;Hopf, J. M.;Woldorff, M. G.
通讯作者：
Woldorff, M. G.
影响因子：
2.9
作者：
Forstmann BU;Brown S;Dutilh G;Neumann J;Wagenmakers EJ
通讯作者：
Wagenmakers EJ
影响因子：
2.9
作者：
Brown, Joshua W.;Braver, Todd S.
通讯作者：
Braver, Todd S.
影响因子：
4.1
作者：
Fillmore, MT;Rush, CR
通讯作者：
Rush, CR