Global epidemiology of systemic lupus erythematosus.
Global epidemiology of systemic lupus erythematosus.
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DOI：
10.1038/s41584-021-00668-1
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发表时间：
2021-09
期刊：
影响因子：
--
通讯作者：
Ramsey-Goldman R
中科院分区：
文献类型：
--
作者：
Barber MRW;Drenkard C;Falasinnu T;Hoi A;Mak A;Kow NY;Svenungsson E;Peterson J;Clarke AE;Ramsey-Goldman R
系统性红斑狼疮（SLE）是一种自身免疫性疾病，主要影响年轻女性。某些种族群体比其他人更容易发生SLE，发病率和死亡率增加。由于人口统计学、环境暴露和社会经济因素的固有差异，SLE的全球发病率和患病率报告差异很大。研究设计和病例定义的差异也导致报告不一致。关于SLE在非洲和澳大拉西亚的发病率知之甚少。识别和弥补流行病学中的这些差距对于了解SLE的全球负担和改善患者结局至关重要。SLE的死亡率仍然比一般人群高出两到三倍。在国际上，系统性红斑狼疮患者常见的死亡原因包括感染和心血管疾病。即使没有新的治疗方法，死亡率也可以通过提高护理质量来降低。本综述主要集中在过去5年的全球流行病学研究，并讨论了SLE的区域发病率和患病率以及死亡的主要原因。
Systemic lupus erythematosus (SLE) is an autoimmune disease with protean manifestations that predominantly affects young women. Certain ethnic groups are more vulnerable than others to developing SLE and experience increased morbidity and mortality. Reports of the global incidence and prevalence of SLE vary widely, owing to inherent variation in population demographics, environmental exposures and socioeconomic factors. Differences in study design and case definitions also contribute to inconsistent reporting. Very little is known about the incidence of SLE in Africa and Australasia. Identifying and remediating such gaps in epidemiology is critical to understanding the global burden of SLE and improving patient outcomes. Mortality from SLE is still two to three times higher than that of the general population. Internationally, the frequent causes of death for patients with SLE include infection and cardiovascular disease. Even without new therapies, mortality can potentially be mitigated with enhanced quality of care. This Review focuses primarily on the past 5 years of global epidemiological studies and discusses the regional incidence and prevalence of SLE and top causes of mortality.
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影响因子：
5.5
作者：
Cortes Verdu, Raul;Pego-Reigosa, Jose M.;Bustabad, Sagrario
通讯作者：
Bustabad, Sagrario
影响因子：
4.7
作者：
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通讯作者：
Fritzler MJ
影响因子：
2.6
作者：
Bossingham, D
通讯作者：
Bossingham, D
影响因子：
3.1
作者：
Bongomin, Felix;Sekimpi, Maria;Kaddumukasa, Mark
通讯作者：
Kaddumukasa, Mark
DOI：
10.1111/j.1445-5994.1993.tb04720.x
发表时间：
1993-12-01
期刊：
AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE
影响因子：
--
作者：
ANSTEY, NM;BASTIAN, I;CURRIE, BJ
通讯作者：
CURRIE, BJ