Cortical correlates of self-generation in verbal paired associate learning.
Cortical correlates of self-generation in verbal paired associate learning.
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DOI：
10.1016/j.brainres.2011.12.020
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发表时间：
2012-02-09
期刊：
影响因子：
2.9
通讯作者：
Szaflarski JP
中科院分区：
文献类型：
--
作者：
Vannest J;Eaton KP;Henkel D;Siegel M;Tsevat RK;Allendorfer JB;Schefft BK;Banks C;Szaflarski JP
行为学研究表明，自我生成的语言信息比阅读（被动学习）更容易被记住。我们使用功能性磁共振成像和配对联想任务来检查自我生成记忆编码的大脑网络。受试者为49名年龄在19 - 62岁的健康英语使用者（30名女性）。在功能磁共振成像任务中，相关的单词对在"阅读"条件下呈现，其中受试者查看两个单词并大声朗读第二个单词，或者"生成"条件，其中第二个单词仅显示第一个字母，受试者被要求生成单词。在每种条件下呈现30个词对。在功能磁共振成像扫描之后，在强迫选择识别任务中，阅读或生成的单词被呈现，每个单词都有两个箔。在识别后测试中，“生成”条件下的单词比“阅读”条件下的单词更正确地识别（生成单词的80.0%对阅读单词的72.0%; t（48）= 5.17，p <0.001）。FMRI显示双侧额下回/额中回（L> R）、前扣带回、尾状核和双侧颞顶枕交界处的生成>读取激活增加。对于“阅读”条件，个体受试者随后更好的记忆表现与双侧楔叶的激活呈正相关。在"生成"条件下，更好的后续记忆表现与左侧上级颞回的激活呈正相关。这些结果表明，自我生成提高了记忆性能，增强皮层激活伴随着自我生成的编码，以及特定大脑网络的招募是自我生成编码的基础。这一发现可能对开发增强记忆能力的程序具有启示意义。
Behavioral studies have shown that verbal information is better retained when it is self-generated rather than read (learned passively). We used fMRI and a paired associates task to examine brain networks underlying self-generated memory encoding. Subjects were 49 healthy English speakers ages 19–62 (30 female). In the fMRI task, related word pairs were presented in a “read” condition, where subjects viewed both words and read the second word aloud, or a “generate” condition, where the second word was presented with only the first letter and the subject was required to generate the word. Thirty word pairs were presented in each condition. After the fMRI scan, words that were read or generated were presented, each with two foils, in a forced-choice recognition task. On the recognition post-test, words from the “generate” condition were more correctly recognized than from the “read” condition (80.0% for generated words versus 72.0% for read words; t(48) = 5.17, p < 0.001). FMRI revealed increased activation for generate>read in inferior/middle frontal gyri bilaterally (L>R), anterior cingulate, and caudate nucleus and the temporo-parietal-occipital junction bilaterally. For the “read” condition, better subsequent memory performance across individual subjects was positively correlated with activation in the cuneus bilaterally. In the “generate” condition, better subsequent memory performance was positively correlated with activation in the left superior temporal gyrus. These results suggest that self-generation improves memory performance, that enhanced cortical activation accompanies self-generated encoding, and that recruitment of a specific brain network underlies self-generated encoding. The findings may have implications for the development of procedures to enhance memory performance.
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DOI：
10.1073/pnas.0504136102
发表时间：
2005-07-05
影响因子：
11.1
作者：
Fox, MD;Snyder, AZ;Raichle, ME
通讯作者：
Raichle, ME
影响因子：
5.7
作者：
Daselaar, SM;Prince, SE;Cabeza, R
通讯作者：
Cabeza, R
影响因子：
5.7
作者：
Hahn, Britta;Ross, Thomas J.;Stein, Elliot A.
通讯作者：
Stein, Elliot A.
影响因子：
2.4
作者：
DiFrancesco, Mark W.;Holland, Scott K.;Szaflarski, Jerzy P.
通讯作者：
Szaflarski, Jerzy P.
影响因子：
14.5
作者：
BOTTINI, G;CORCORAN, R;FRITH, CD
通讯作者：
FRITH, CD