Developmental Associations between Neurovascularization and Microglia Colonization.
Developmental Associations between Neurovascularization and Microglia Colonization.
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DOI：
10.3390/ijms25021281
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发表时间：
2024-01-20
影响因子：
5.6
通讯作者：
Harry, G. Jean
中科院分区：
文献类型：
--
作者：
Harry, G. Jean
神经系统的小胶质细胞定植和血管浸润的时间和空间模式意味着在神经系统发育的早期阶段的关键相关作用。除了涵盖大脑发育过程中各种小胶质细胞的各种作用的现有评论外，当前的评论将重点放在神经系统与蛋黄囊衍生的巨噬细胞和血管化的神经系统定植之间的发育本体发育和相互依存。更好地了解这两个过程的时间和相互依存关系将显着有助于解释有关早期开发过程中任何一种过程的变化所产生的数据。此外，这种知识应提供一个框架，以了解早期妊娠环境的影响以及遗传学，疾病，疾病或暴露对早期发展神经系统的影响以及长期和终身影响的潜力。
The temporal and spatial pattern of microglia colonization and vascular infiltration of the nervous system implies critical associated roles in early stages of nervous system development. Adding to existing reviews that cover a broad spectrum of the various roles of microglia during brain development, the current review will focus on the developmental ontogeny and interdependency between the colonization of the nervous system with yolk sac derived macrophages and vascularization. Gaining a better understanding of the timing and the interdependency of these two processes will significantly contribute to the interpretation of data generated regarding alterations in either process during early development. Additionally, such knowledge should provide a framework for understanding the influence of the early gestational environmental and the impact of genetics, disease, disorders, or exposures on the early developing nervous system and the potential for long-term and life-time effects.
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影响因子：
3.4
作者：
Bergström T;Forsberg-Nilsson K
通讯作者：
Forsberg-Nilsson K
影响因子：
6.2
作者：
Arnoux, Isabelle;Hoshiko, Maki;Audinat, Etienne
通讯作者：
Audinat, Etienne
影响因子：
2.5
作者：
DIAZARAYA, CM;PROVIS, JM;BILLSON, FA
通讯作者：
BILLSON, FA
影响因子：
20.3
作者：
Fantin, Alessandro;Vieira, Joaquim M.;Ruhrberg, Christiana
通讯作者：
Ruhrberg, Christiana
影响因子：
3.5
作者：
Ek, C. Joakim;Wong, Annamae;Saunders, Norman R.
通讯作者：
Saunders, Norman R.