Microchip electrophoretic separation systems for biomedical and pharmaceutical analysis.

Microchip electrophoretic separation systems for biomedical and pharmaceutical analysis.
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用于生物医学和药物分析的微芯片电泳分离系统。

DOI:
10.1016/s0928-0987(01)00153-1
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发表时间:
2001
期刊:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
影响因子:
--
通讯作者:
S. Lunte
S. Lunte
中科院分区:
--
文献类型:
--
作者:
A. Gawron;R. Martin;S. Lunte

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介绍了微芯片毛细管电泳(CE)系统在生物医学和药物分析中的应用。讨论了系统的制造、仪表和操作。概述了应用,包括四个主要领域:DNA测序,遗传分析,免疫分析,蛋白质和肽分析。这些系统有可能极大地改变生化分析的执行方式。
The application of microchip capillary electrophoresis (CE) systems to biomedical and pharmaceutical analysis is described and reviewed. Fabrication, instrumentation, and operation of the systems are discussed. An overview of applications is presented, covering four main areas: DNA sequencing, genetic analysis, immunoassays, and protein and peptide analysis. These systems have the potential to dramatically change the way that biochemical analyses are performed.
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