Culex tarsalis is a competent vector species for Cache Valley virus.
Culex tarsalis is a competent vector species for Cache Valley virus.
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DOI：
10.1186/s13071-018-3103-2
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发表时间：
2018-09-20
影响因子：
3.2
通讯作者：
Vanlandingham DL
中科院分区：
文献类型：
--
作者：
Ayers VB;Huang YS;Lyons AC;Park SL;Higgs S;Dunlop JI;Kohl A;Alto BW;Unlu I;Blitvich BJ;Vanlandingham DL
卡奇谷病毒(CVV)是一种由蚊子传播的正丁型病毒，在北美流行。该病毒是一种重要的农业病原体，可导致反刍动物，尤其是绵羊的流产和胚胎死亡。近年来，由于严重的嗜神经疾病的报道，CVV在人类公共卫生中的重要性有所增加。然而，将病毒传播给人类的蚊子种类仍有待确定。本研究对三种对公共卫生有重要意义的库蚊：淡色库蚊、库蚊、库蚊的媒介能力进行了研究。Tarsalis和Cx.Ququiefasciatus，以确定负责CVV从病毒宿主传播到人类的潜在桥梁载体物种。观察了不同品系库蚊对CVV的敏感性差异。经口感染可导致塔氏库蚊的感染和传播，而Cx。Piniens和Cx.对CVV高度耐药。CX感染者唾液中病毒RNA的检测Tarsalis提供了支持其作为合格媒介的作用的证据。我们的研究提供了对CVV传播周期的进一步了解，并鉴定了Cx。作为一种称职的媒介的酒石。
Cache Valley virus (CVV) is a mosquito-borne orthobunyavirus endemic in North America. The virus is an important agricultural pathogen leading to abortion and embryonic lethality in ruminant species, especially sheep. The importance of CVV in human public health has recently increased because of the report of severe neurotropic diseases. However, mosquito species responsible for transmission of the virus to humans remain to be determined. In this study, vector competence of three Culex species mosquitoes of public health importance, Culex pipiens, Cx. tarsalis and Cx. quinquefasciatus, was determined in order to identify potential bridge vector species responsible for the transmission of CVV from viremic vertebrate hosts to humans. Variation of susceptibility to CVV was observed among selected Culex species mosquitoes tested in this study. Per os infection resulted in the establishment of infection and dissemination in Culex tarsalis, whereas Cx. pipiens and Cx. quinquefasciatus were highly refractory to CVV. Detection of viral RNA in saliva collected from infected Cx. tarsalis provided evidence supporting its role as a competent vector. Our study provided further understanding of the transmission cycles of CVV and identifies Cx. tarsalis as a competent vector.
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影响因子：
2.1
作者：
Andreadis, Theodore G.;Armstrong, Philip M.;Main, Andrew J.
通讯作者：
Main, Andrew J.
DOI：
10.4269/ajtmh.1986.35.429
发表时间：
1986-03-01
影响因子：
3.3
作者：
CALISHER, CH;FRANCY, DB;MCLEAN, RG
通讯作者：
MCLEAN, RG
影响因子：
56.9
作者：
HOLDEN, P;HESS, AD
通讯作者：
HESS, AD
影响因子：
2.1
作者：
Huang, Yan-Jang S.;Harbin, Julie N.;Vanlandingham, Dana L.
通讯作者：
Vanlandingham, Dana L.
影响因子：
2.1
作者：
Blackmore, CGM;Blackmore, MS;Grimstad, PR
通讯作者：
Grimstad, PR