Facilitated acquisition of eyeblink conditioning in those vulnerable to anxiety disorders.
Facilitated acquisition of eyeblink conditioning in those vulnerable to anxiety disorders.
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DOI：
10.3389/fnhum.2013.00348
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发表时间：
2013
影响因子：
2.9
通讯作者：
Servatius RJ
中科院分区：
文献类型：
--
作者：
Caulfield MD;McAuley JD;Servatius RJ
行为抑制(BI)增加了患焦虑症的易感性，其典型特征是对新对象、新人和新情景的回避和回避。本研究考虑了BI与气质风险因素的关系，如特质焦虑和经典条件眨眼反应的习得率。对174名健康大学生(平均年龄20.3岁，女性占71.8%)进行了状态-特质焦虑问卷和BI自评量表的测试，该量表包括成人和回溯性行为抑制量表(AMBI/RMBI)和同时和回溯性抑制自我报告(CSRI/RSRI)。参与者随后接受了标准延迟经典眨眼条件反射，包括45次试验，500毫秒的CS重叠，并与10毫秒的喷气US共同终止。在AMBI和特质焦虑量表上得分较高的人，但在其他指标上没有表现出比得分较低的人更快地获得条件眨眼反应。结果支持促进获得内部刺激关系和焦虑风险之间的关系，并表明一些评估焦虑脆弱性的指标比其他指标更好地捕捉到这种关系。
Behavioral inhibition (BI) increases vulnerability to develop anxiety disorders and is typified by avoidance and withdrawal from novel objects, people, and situations. The present study considered the relationship between BI and temperamental risk factors, such as trait anxiety and acquisition rate of a classically conditioned eyeblink response. One-hundred seventy-four healthy undergraduate students (mean age 20.3 years, 71.8% female) were given the State-Trait Anxiety Inventory and a battery of self-report measures of BI consisting of the Adult and Retrospective Measures of Behavioral Inhibition (AMBI/RMBI) and the Concurrent and Retrospective Self Report of Inhibition (CSRI/RSRI). Participants then underwent standard delay classical eyeblink conditioning consisting of 45 trials with a 500-ms CS overlapping and co-terminating with a 10-ms airpuff US. Individuals with higher scores on the AMBI and Trait Anxiety Inventory, but not the other measures, showed faster acquisition of a conditioned eyeblink response than individuals with lower scores. Results support a relationship between facilitated acquisition of inter-stimulus relationships and risk for anxiety, and suggest that some measures assessing anxiety vulnerability better capture this relationship than others.
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DOI：
10.3109/10253890.2011.578184
发表时间：
2012-01
期刊：
Stress (Amsterdam, Netherlands)
影响因子：
--
作者：
Myers CE;Vanmeenen KM;McAuley JD;Beck KD;Pang KC;Servatius RJ
通讯作者：
Servatius RJ
影响因子：
1.6
作者：
Beck, Kevin D.;McLaughlin, Joselyn;Servatius, Richard J.
通讯作者：
Servatius, Richard J.
影响因子：
120.7
作者：
Binder, Elisabeth B.;Bradley, Rebekah G.;Ressler, Kerry J.
通讯作者：
Ressler, Kerry J.
影响因子：
--
作者：
Kessler, RC;Berglund, P;Walters, EE
通讯作者：
Walters, EE
影响因子：
11.3
作者：
Gladstone, G;Parker, G
通讯作者：
Parker, G