Influence of social relationship domains and their combinations on incident dementia: a prospective cohort study.
Influence of social relationship domains and their combinations on incident dementia: a prospective cohort study.
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DOI：
10.1136/jech-2017-209811
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发表时间：
2018-01
影响因子：
6.3
通讯作者：
Kondo K
中科院分区：
文献类型：
--
作者：
Saito T;Murata C;Saito M;Takeda T;Kondo K
社会关系由相互关联但又截然不同的维度组成。目前尚不清楚这些区域是如何独立地导致偶发性痴呆的。这项大规模的前瞻性队列研究考察了社区老年人的社会关系领域及其组合与痴呆症事件之间的关系。我们分析了居住在日本爱知县的13名 984名65岁以上没有 长期护理需求的社区成年人的数据。根据长期护理保险记录对偶发痴呆症进行评估，从2003年进行的基线调查开始，跟踪了3436天。三个社会关系领域(社会支持、社会网络和社会活动)被进一步划分为八个子域。使用与痴呆症事件显著相关的社会关系领域计算社会关系多样性得分。Cox比例风险模型显示，已婚、与家人交换支持、与朋友有联系、参加社区小组和从事有偿工作与患痴呆症的可能性较低、控制协变量和其他社会关系领域有关。多样性得分从0.001到5与痴呆症的发病率呈线性相关(p<；0.001)，得分最高的人患痴呆症的可能性比得分最低的人低46%。我们的发现揭示了与偶发痴呆症负相关的五个社会关系子域，这表明通过加强这些社会关系可能会预防痴呆症。未来的研究应该检查每个社会关系领域和偶发痴呆症之间的独立路径。
Social relationships consist of mutually related but distinct dimensions. It remains unclear how these domains independently contribute to incident dementia. This large-scale, prospective cohort study examines associations between the social relationship domains as well as their combinations and incident dementia among community-dwelling older adults. We analysed data from 13 984 community-dwelling adults aged 65+ without long-term care needs living in Aichi prefecture in Japan. Incident dementia was assessed based on the Long-term Care Insurance records, followed for 3436 days from the baseline survey conducted in 2003. Three social relationships domains (social support, social networks and social activities) were further divided into a total of eight subdomains. A social relationship diversity score was calculated using the social relationship domains which were significantly related to incident dementia. A Cox proportional hazards model showed that being married, exchanging support with family members, having contact with friends, participating in community groups and engaging in paid work were related to a lower likelihood of developing incident dementia, controlling for covariates and other social relationship domains. The diversity scores, ranging from 0 to 5, were linearly associated with incident dementia (p<0.001), and those who scored highest were 46% less likely to develop incident dementia compared with those in the lowest category. Our findings revealed five social relationship subdomains which were negatively related to incident dementia, suggesting that dementia may potentially be prevented by enhancing these social relationships. Future studies should examine independent pathways between each social relationship domain and incident dementia.
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DOI：
10.1017/s1355617711000531
发表时间：
2011-11
影响因子：
2.6
作者：
James, Bryan D.;Wilson, Robert S.;Barnes, Lisa L.;Bennett, David A.
通讯作者：
Bennett, David A.
影响因子：
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作者：
Lee SH;Kim YB
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Kim YB
影响因子：
168.9
作者：
Fratiglioni, L;Wang, HX;Winblad, B
通讯作者：
Winblad, B
影响因子：
7
作者：
Schafer, JL;Graham, JW
通讯作者：
Graham, JW
影响因子：
2
作者：
Meguro, Kenichi;Tanaka, Naofumi;Ouchi, Yoshitaka
通讯作者：
Ouchi, Yoshitaka