Global view of the functional molecular organization of the avian cerebrum: mirror images and functional columns.
Global view of the functional molecular organization of the avian cerebrum: mirror images and functional columns.
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DOI：
10.1002/cne.23404
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发表时间：
2013-11
影响因子：
2.5
通讯作者：
Wada, Kazuhiro
中科院分区：
文献类型：
--
作者：
Jarvis, Erich D.;Yu, Jing;Rivas, Miriam V.;Horita, Haruhito;Feenders, Gesa;Whitney, Osceola;Jarvis, Syrus C.;Jarvis, Electra R.;Kubikova, Lubica;Puck, Ana E. P.;Siang-Bakshi, Connie;Martin, Suzanne;McElroy, Michael;Hara, Erina;Howard, Jason;Pfenning, Andreas;Mouritsen, Henrik;Chen, Chun-Chun;Wada, Kazuhiro
关键词：
基于对鸟类23个脑区中52个组成性表达或行为调控基因的定量聚类分析，我们提出了鸟类端脑组织的整体观点。组成型表达基因的模式揭示了三个主要细胞群的部分镜像组织，这些细胞群包裹在心室和相邻层的上方、周围和下方。行为调控基因的模式揭示了这些细胞群边界上的功能性激活柱，让人想起哺乳动物皮层的层柱。鸟类功能调节柱有两种类型：脑室和相关的mesopallial层，由我们修订的背侧mesopallium，hyperpallium，和intercalated hyperpallium形成的;和脑室以下，由我们修订的腹侧mesopallium，nidopallium，和intercalated nidopallium形成的。基于这些发现和已知的连通性，我们提出，鸟类palpalpal有四个主要的细胞群类似于哺乳动物皮层和杏仁核的某些部分：1）初级感觉输入人口（intercalated palpal）; 2）二级intrapallial人口（nidopallial/hyperpalpal）; 3）三级intrapallial人口（mesopallial）;和4）四级输出人口（arcopallial）。每个种群都贡献了部分控制不同感觉或运动系统的列。我们认为，这种组织的细胞群的形式通过扩展连续的发育细胞域，包裹侧脑室和其延伸通过中间的mesopallium。我们认为，侧脑室及其相关的中皮层的位置导致了一个概念上的障碍，以识别相关的细胞群跨越其边界，从而混淆了我们的理解与哺乳动物的同源性。
Based on quantitative cluster analyses of 52 constitutively expressed or behaviorally regulated genes in 23 brain regions, we present a global view of telencephalic organization of birds. The patterns of constitutively expressed genes revealed a partial mirror image organization of three major cell populations that wrap above, around, and below the ventricle and adjacent lamina through the mesopallium. The patterns of behaviorally regulated genes revealed functional columns of activation across boundaries of these cell populations, reminiscent of columns through layers of the mammalian cortex. The avian functionally regulated columns were of two types: those above the ventricle and associated mesopallial lamina, formed by our revised dorsal mesopallium, hyperpallium, and intercalated hyperpallium; and those below the ventricle, formed by our revised ventral mesopallium, nidopallium, and intercalated nidopallium. Based on these findings and known connectivity, we propose that the avian pallium has four major cell populations similar to those in mammalian cortex and some parts of the amygdala: 1) a primary sensory input population (intercalated pallium); 2) a secondary intrapallial population (nidopallium/hyperpallium); 3) a tertiary intrapallial population (mesopallium); and 4) a quaternary output population (the arcopallium). Each population contributes portions to columns that control different sensory or motor systems. We suggest that this organization of cell groups forms by expansion of contiguous developmental cell domains that wrap around the lateral ventricle and its extension through the middle of the mesopallium. We believe that the position of the lateral ventricle and its associated mesopallium lamina has resulted in a conceptual barrier to recognizing related cell groups across its border, thereby confounding our understanding of homologies with mammals.
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影响因子：
3.7
作者：
Feenders, Gesa;Liedvogel, Miriam;Rivas, Miriam;Zapka, Manuela;Horita, Haruhito;Hara, Erina;Wada, Kazuhiro;Mouritsen, Henrik;Jarvis, Erich D.
通讯作者：
Jarvis, Erich D.
影响因子：
2.5
作者：
Atoji, Y;Wild, JM
通讯作者：
Wild, JM
影响因子：
5.3
作者：
Carney, Rosalind S. E.;Alfonso, Teresa B.;Corbin, Joshua G.
通讯作者：
Corbin, Joshua G.
DOI：
10.1098/rspb.2008.1138
发表时间：
2009-01-22
影响因子：
4.7
作者：
Hara, Erina;Kubikova, Lubica;Jarvis, Erich D.
通讯作者：
Jarvis, Erich D.
影响因子：
3.7
作者：
Abellan, Antonio;Menuet, Arnaud;Retaux, Sylvie
通讯作者：
Retaux, Sylvie