Telephone-based assessments to minimize missing data in longitudinal depression trials: a project IMPACTS study report.
Telephone-based assessments to minimize missing data in longitudinal depression trials: a project IMPACTS study report.
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DOI：
10.1016/j.cct.2008.08.001
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发表时间：
2009-01
影响因子：
2.2
通讯作者：
Flood A
中科院分区：
文献类型：
--
作者：
Claassen C;Kurian B;Trivedi MH;Grannemann BD;Tuli E;Pipes R;Preston AM;Flood A
临床疗效和有效性试验数据的缺失仍然是研究结果有效性的主要威胁。本报告的目的是描述为确保完成对参与治疗重度抑郁症的纵向、重复措施研究的公共精神卫生部门受试者的结果评估而制定的方法。我们开发了纵向评估程序，包括基于电话的临床医生访谈，以尽量减少面对面评估程序中经常遇到的缺失数据。制定了预先计划的多步骤策略，以确保数据收集的完整性。该程序包括在基线时获取多项患者联系信息，对工作人员和患者进行有关评估目的的仔细教育，建立良好的患者关系，最后灵活和坚持电话预约，以确保完成电话随访评估。在实施研究之前，还建立了完善的行政和组织结构。在入组的504名受试者中，有310名完成了52周的电话随访评估，主要结局的评估完成率为96.8%。通过利用基于电话的随访程序和适应我们易于使用的预定义多步骤方法，研究人员可以在纵向研究中最大限度地保留患者数据。
Missing data in clinical efficacy and effectiveness trials continue to be a major threat to the validity of study findings. The purpose of this report is to describe methods developed to ensure completion of outcome assessments with public mental health sector subjects participating in a longitudinal, repeated measures study for the treatment of major depressive disorder. We developed longitudinal assessment procedures that included telephone-based clinician interviews in order to minimize missing data commonly encountered with face-to-face assessment procedures. A pre-planned, multi-step strategy was developed to ensure completeness of data collection. The procedure included obtaining multiple pieces of patient contact information at baseline, careful education of both staff and patients concerning the purpose of assessments, establishing good patient rapport, and finally being flexible and persistent with phone appointments to ensure the completion of telephone-based follow-up assessments. A well-developed administrative and organizational structure was also put in place prior to study implementation. The assessment completion rate for the primary outcome for 310 of 504 subjects who enrolled and completed 52 weeks (at the time of manuscript) of telephone-based follow-up assessments was 96.8%. By utilizing telephone-based follow-up procedures and adapting our easy-to-use pre-defined multi-step approach, researchers can maximize patient data retention in longitudinal studies.
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影响因子：
4.2
作者：
Midanik, LT;Greenfield, TK
通讯作者：
Greenfield, TK
影响因子：
6.9
作者：
Evans, M;Kessler, D;Sharp, D
通讯作者：
Sharp, D
影响因子：
4.2
作者：
Cottler, LB;Compton, WM;Claverie, D
通讯作者：
Claverie, D
影响因子：
2.9
作者：
Hepner, KA;Brown, JA;Hays, RD
通讯作者：
Hays, RD
DOI：
10.1177/070674379303800801
发表时间：
1993-10-01
影响因子：
4
作者：
FOURNIER, L;KOVESS, V
通讯作者：
KOVESS, V