Identification of coronaviruses in dogs that segregate separately from the canine coronavirus genotype.
Identification of coronaviruses in dogs that segregate separately from the canine coronavirus genotype.
复制标题
DOI：
10.1016/s0166-0934(02)00246-x
复制
发表时间：
2003-03
影响因子：
3.1
通讯作者：
Buonavoglia C
中科院分区：
文献类型：
--
作者：
Pratelli A;Martella V;Pistello M;Elia G;Decaro N;Buonavoglia D;Camero M;Tempesta M;Buonavoglia C
本文报道了16份犬冠状病毒(CCoV)样本的遗传多样性。样本取自生活在不同地区的自然感染的幼崽。序列数据来自M基因以及pol1a和pol1b区域。确定了这些序列和以前发表的序列之间的系统发育关系。犬类样本被分成两个独立的簇。第一类群的样本与CCoV基因的参考毒株混合，因此可以归类为该基因。第二类分别与冠状病毒和猫冠状病毒的基因型别分开，因此这些样本可能代表遗传异常值。通过对来自多个基因组区域的核苷酸和氨基酸序列的重复系统发育分析，证实了分类结果的可靠性。
The genetic diversity of 16 canine coronavirus (CCoV) samples is described. Samples were obtained from pups infected naturally living in different areas. Sequence data were obtained from the M gene and pol1a and pol1b regions. The phylogenetic relationships among these sequences and sequences published previously were determined. The canine samples segregated in two separate clusters. Samples of the first cluster were intermingled with reference strains of CCoV genotype and therefore could be assigned to this genotype. The second cluster segregated separately from CCoV and feline coronavirus genotypes and therefore these samples may represent genetic outliers. The reliability of the classification results was confirmed by repeating the phylogenetic analysis with nucleotide and amino acid sequences from multiple genomic regions.
登录
查看更多内容
影响因子：
1.2
作者：
HOHDATSU, T;OKADA, S;KOYAMA, H
通讯作者：
KOYAMA, H
影响因子：
5.4
作者：
de Haan, CAM;Vennema, H;Rottier, PJM
通讯作者：
Rottier, PJM
影响因子：
9.4
作者：
HERREWEGH, AAPM;DEGROOT, RJ;ROTTIER, PJM
通讯作者：
ROTTIER, PJM
影响因子：
1.2
作者：
Bandai, C;Ishiguro, S;Mochizuki, M
通讯作者：
Mochizuki, M
影响因子：
2.7
作者：
JIA, W;KARACA, K;NAQI, SA
通讯作者：
NAQI, SA