Prevalence, awareness, treatment and control of dyslipidemia in older persons in urban and rural population in the Astana region, Kazakhstan.
Prevalence, awareness, treatment and control of dyslipidemia in older persons in urban and rural population in the Astana region, Kazakhstan.
复制标题
DOI：
10.1186/s12889-017-4629-5
复制
发表时间：
2017-08-11
影响因子：
4.5
通讯作者：
Bobak M
中科院分区：
文献类型：
--
作者：
Supiyev A;Nurgozhin T;Zhumadilov Z;Peasey A;Hubacek JA;Bobak M
尽管前苏联中亚共和国的心血管疾病死亡率很高，但关于主要危险因素（包括血脂）的信息有限。我们调查了哈萨克斯坦城市和农村人口中血脂浓度受损的患病率、对高胆固醇血症的认识、治疗和控制，以及与这些指标相关的因素。我们对随机城市和农村人口样本（州首府阿斯塔纳和Akmol村）进行了横断面研究。研究对象为50-74岁的男性和女性；共有954名成年人参与调查（应答率59%）。测量血清总胆固醇、低密度脂蛋白和高密度脂蛋白胆固醇和甘油三酯浓度以及一系列其他心血管危险因素。高胆固醇血症（总胆固醇≥6.2 mmol/l）的总患病率为37%；在高胆固醇血症患者中，57%的人知道自己的病情，41%的人服用药物，23%的人总胆固醇<6.2 mmol/l （4.5% <5 mmol/l）。城市地区高胆固醇血症的患病率、认知度、治疗和控制水平均高于农村地区。同样，在城市人口中，特定脂质组分浓度受损的受试者比例也相当高。与其他协变量的大多数关联都在预期的方向上。该研究发现，哈萨克人口中血脂异常的患病率相对较高，而城市地区的血脂状况较差。这些明显的城乡差异可能与城市化、相关的营养转变和获得保健有关。本文的在线版本（doi:10.1186/s12889-017-4629-5）包含补充材料，可供授权用户使用。
Despite high cardiovascular mortality in Central Asian republics of the former Soviet Union, there is limited information about major risk factors, including blood lipids. We investigated the prevalence of impaired concentrations of blood lipids, the awareness, treatment and control of hypercholesterolemia, and factors associated with these indicators in urban and rural populations in Kazakhstan. We conducted a cross-sectional study of random urban and rural population samples (the state capital Astana and Akmol village). Men and women aged 50–74 years were examined; a total of 954 adults participated (response rate 59%). Serum concentrations of total, LDL and HDL cholesterol and triglycerides and a range of other cardiovascular risk factors were measured. The overall prevalence of hypercholesterolemia (total cholesterol ≥6.2 mmol/l) was 37%; among subjects with hypercholesterolemia, 57% were aware of their condition, 41% took medication and 23% had total cholesterol <6.2 mmol/l (4.5% <5 mmol/l). The prevalence, awareness, treatment, and control of hypercholesterolemia were all higher in the urban than the rural area. Similarly, the proportions of subjects with impaired concentrations of specific lipids fractions were also considerably higher in the urban population. Most associations with other covariates were in the expected direction. This study found relatively high prevalence of dyslipidemia in the Kazakh population, and the blood lipid profile was less favourable in the urban area. These pronounced urban–rural differences may be related to urbanization, the associated nutrition transition and to access to health care. The online version of this article (doi:10.1186/s12889-017-4629-5) contains supplementary material, which is available to authorized users.
登录
查看更多内容
影响因子：
4.4
作者：
Bayram, Fahri;Kocer, Derya;Gedik, Vedia
通讯作者：
Gedik, Vedia
影响因子：
2.1
作者：
Hubacek, J. A.;Stanek, V.;Pitha, J.
通讯作者：
Pitha, J.
影响因子：
2.9
作者：
Omboni S;Carabelli G;Ghirardi E;Carugo S
通讯作者：
Carugo S
影响因子：
2.9
作者：
Choudhury, Kamrun Nahar;Mainuddin, Akm;Islam, Sheikh Mohammed Shariful
通讯作者：
Islam, Sheikh Mohammed Shariful
影响因子：
--
作者：
Barter, Philip
通讯作者：
Barter, Philip