Cohort Differences in Cognitive Aging in the Longitudinal Aging Study Amsterdam.
Cohort Differences in Cognitive Aging in the Longitudinal Aging Study Amsterdam.
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DOI：
10.1093/geronb/gbw129
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发表时间：
2018-09-20
期刊：
影响因子：
--
通讯作者：
Comijs H
中科院分区：
文献类型：
--
作者：
Brailean A;Huisman M;Prince M;Prina AM;Deeg DJH;Comijs H
本研究的目的是研究队列差异的认知性能和变化率的情景记忆，处理速度，归纳推理，一般认知性能和调查是否这些队列效应可以解释教育程度。第一个队列（N = 705）出生于1920年至1930年，而第二个队列（N = 646）出生于1931年至1941年。两个出生队列的基线年龄为65至75岁，并在3年和6年后进行随访。使用线性混合模型分析数据。晚出生的队列在基线时具有更好的一般认知表现，归纳推理和处理速度，但在调整教育后，归纳推理和一般认知表现的队列差异消失了。较晚出生的队列在处理速度方面表现出更大的下降。记忆力下降在较早出生的队列中更陡峭，但仅在时间1至时间3进行相同的记忆力测试时。教育并不能解释认知能力下降的群体差异。晚出生的队列在某些认知能力方面表现出更好的初始表现，但与早出生的队列相比，随着时间的推移，认知能力并没有得到更好的保护。这些发现对健康的认知老化具有启示意义。
This study aims to examine cohort differences in cognitive performance and rates of change in episodic memory, processing speed, inductive reasoning, and general cognitive performance and to investigate whether these cohort effects may be accounted for by education attainment. The first cohort (N = 705) was born between 1920 and 1930, whereas the second cohort (N = 646) was born between 1931 and 1941. Both birth cohorts were aged 65 to 75 years at baseline and were followed up 3 and 6 years later. Data were analyzed using linear mixed models. The later born cohort had better general cognitive performance, inductive reasoning, and processing speed at baseline, but cohort differences in inductive reasoning and general cognitive performance disappeared after adjusting for education. The later born cohort showed steeper decline in processing speed. Memory decline was steeper in the earlier born cohort but only from Time 1 to Time 3 when the same memory test was administered. Education did not account for cohort differences in cognitive decline. The later born cohort showed better initial performance in certain cognitive abilities, but no better preservation of cognitive abilities overtime compared with the earlier born cohort. These findings carry implications for healthy cognitive aging.
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影响因子：
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作者：
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通讯作者：
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作者：
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